PDF(Pubmed)
Abstract：
FLA-related conditions are a rare medical occurrence. Despite their rarity, they are considered a public health concern for two reasons: the absence of a regular treatment regimen in the case of central nervous system infections and the fast progression of the symptoms leading to fatal outcomes. A total of 358 articles were retrieved from different databases (91 from PubMed, 26 from NCBI, 138 from Academia, 102 from Science Direct, and one from IJMED). 7 (46.6%) clinical cases came from Egypt, 2 (13.3%) cases of FLA infection came from Nigeria, 3 (20%) cases came from the Gambia, and 1 (6.6%) case was reported from African countries like Algeria, Tunisia, South Africa, and Zambia. Medical conditions caused by free-living amoeba are considered significant public health concerns. These ubiquitous organisms can cause both fatal and debilitating health conditions. Immediate diagnosis of cases and proper hygienic practices are necessary to provide direct medical intervention. They may be the key to reducing the morbidity and mortality rates from FLA-acquired infections. Although several government-led initiatives have been implemented to mitigate a plethora of parasitic diseases, the case of FLA-related conditions in African countries has yet to be realized.
摘要：
FLA相关疾病是一种罕见的医学事件。尽管它们很少,它们被认为是公共卫生问题,原因有二:在中枢神经系统感染的情况下,缺乏常规治疗方案,以及症状的快速进展导致致命结局.从不同的数据库共检索到358篇文章(91来自PubMed，26来自NCBI，138来自学术界，102来自科学直接，和一个来自IJMED）。7例（46.6%）来自埃及，2例（13.3%）FLA感染病例来自尼日利亚，3例（20％）来自冈比亚，1例（6.6%）来自阿尔及利亚等非洲国家，突尼斯,南非,赞比亚。由自由生活的变形虫引起的医疗状况被认为是重大的公共卫生问题。这些无处不在的生物会导致致命和衰弱的健康状况。必须立即诊断病例和适当的卫生习惯，以提供直接的医疗干预。它们可能是降低FLA获得性感染的发病率和死亡率的关键。尽管已经实施了一些政府主导的举措来减轻过多的寄生虫病，非洲国家与FLA相关的情况尚未实现。
