Abstract：
The widespread occurrence of bacterial infections and their increased resistance to antibiotics has led to the development of antimicrobial coatings for multiple medical implants. Owing to their desirable properties, gold nanoparticles (AuNPs) have been developed as antibacterial agents. This systematic investigation sought to analyze the antibacterial effects of implant material surfaces modified with AuNPs. The data from 27 relevant studies were summed up. The included articles were collected from September 2011 to September 2021. According to the retrieved literature, we found that medical implants modified by AuNPs have good antibacterial effects against gram-positive and gram-negative bacteria, and the antibacterial effects would be improved by near-infrared (NIR) radiation.
摘要：
细菌感染的广泛发生及其对抗生素的抗性增加导致了用于多种医疗植入物的抗微生物涂层的开发。由于它们理想的特性，金纳米颗粒(AuNP)已经被开发为抗菌剂。这项系统的研究旨在分析AuNP修饰的植入物材料表面的抗菌作用。总结了27项相关研究的数据。所包括的文章收集时间为2011年9月至2021年9月。根据检索到的文献，我们发现AuNPs修饰的医用植入物对革兰氏阳性菌和革兰氏阴性菌具有良好的抗菌作用，并且通过近红外（NIR）辐射可以改善抗菌效果。
