关键词: cervical lymph nodes intra-parotid lymph nodes metastasis parotid carcinoma

来  源:   DOI:10.3390/life12122053

Abstract:
The parotid gland contains intra-glandular lymph nodes, the distribution of which is crucial for understanding the pathogenesis of intra-parotid lymph node metastases of parotid carcinoma and other head and neck carcinomas. Positive intra-parotid lymph node metastasis predicts the risk of positive cervical nodal metastasis. It is important to establish whether prophylactic neck dissection, including intra-parotid lymph nodes, contributes to treatment outcomes. The presence or absence of intra-parotid lymph nodes or metastasis-positive lymph nodes warrants further study. A preoperative diagnosis by imaging and fine-needle aspiration cytology of intra-parotid lymph nodes is difficult. Although intraoperative frozen section biopsy is performed during surgery, it is challenging to identify intra-parotid lymph nodes. The number of lymph nodes was the largest (47%) in the lower half of the superficial lobe, with 35% of nodes being concentrated in the inferior part of the cervicofacial branch, i.e., the lower pole of the parotid gland. Therefore, superficial parotidectomy and lower pole lobectomy need to be performed in cases in which a malignant tumor localizes to the superficial lobe or a lower pole. When intra-parotid lymph node metastases are detected during surgery, selective neck dissection (at least levels II and III) needs to be simultaneously performed.
摘要:
腮腺含有腺内淋巴结,其分布对于了解腮腺癌和其他头颈部癌的腮腺内淋巴结转移的发病机制至关重要。腮腺内淋巴结转移阳性预测颈淋巴结转移阳性的风险。重要的是要确定是否预防性颈清扫术,包括腮腺内淋巴结,有助于治疗结果。腮腺内淋巴结或转移阳性淋巴结的存在与否值得进一步研究。通过影像学和腮腺内淋巴结的细针穿刺细胞学检查进行术前诊断很困难。虽然术中冰冻切片活检是在手术过程中进行的,识别腮腺内淋巴结具有挑战性。浅叶下半部淋巴结数目最多(47%),35%的淋巴结集中在颈面部分支的下部,即,腮腺的下极。因此,如果恶性肿瘤位于浅表叶或下极,则需要进行浅表腮腺切除术和下极叶切除术。当在手术过程中检测到腮腺内淋巴结转移时,选择性颈清扫术(至少II级和III级)需要同时进行.
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