METHODS: Electronic databases were searched for all studies on spinal meningiomas dating from 2000 and onward. Findings of matching studies were pooled to strengthen the current body of evidence.
RESULTS: A total of 104 studies were included. The majority of patients were female (72.83%), elderly (peak decade: seventh), and had a world health organization (WHO) grade 1 tumor (95.7%). Interestingly, the minority of pediatric patients had a male overrepresentation (62.0% vs. 27.17%) and higher-grade tumors (33.3% vs. 4.3%). Sensory and motor dysfunction and pain were the most common presenting symptoms. Despite a handful of studies reporting promising findings associated with the use of non-surgical treatment options, the literature still suffers from contradictory results and limitations of study designs.
CONCLUSIONS: Elderly females with WHO grade 1 tumors constituted the stereotypical type of patient. Compared to surgical alternatives, the evidence for the use of non-surgical treatments is still relatively weak.
方法:在电子数据库中搜索了2000年及以后关于脊髓脑膜瘤的所有研究。对匹配研究的结果进行了汇总,以加强当前的证据。
结果:共纳入104项研究。大多数患者为女性(72.83%),老年人(高峰十年:第七),并且患有世界卫生组织(WHO)1级肿瘤(95.7%)。有趣的是,少数儿科患者的男性比例过高(62.0%vs.27.17%)和高级别肿瘤(33.3%vs.4.3%)。感觉和运动功能障碍和疼痛是最常见的症状。尽管少数研究报告了与使用非手术治疗方案相关的有希望的发现,文献仍然存在矛盾的结果和研究设计的局限性。
结论:患有WHO1级肿瘤的老年女性构成了患者的刻板类型。与手术替代方案相比,使用非手术治疗的证据仍然相对薄弱.