Abstract：
Syringomatous adenoma of the nipple is a rare benign infiltrative neoplasm that was first described in 1983. At the time of this writing, a literature search revealed no cases of syringomatous adenoma of the nipple in association with invasive carcinoma of the breast. We report a case of syringomatous adenoma of the nipple in a 40-year old female who also had bilateral invasive ductal carcinoma and ductal carcinoma in situ of the breasts. Syringomatous adenomas of the nipple have been postulated to originate from eccrine structures of the nipple due to their microscopic similarity to other tumors of eccrine origin, such as syringomatous carcinoma. However, their exact origin is uncertain. Despite their benign behavior, they usually demonstrate an infiltrative and expansile proliferation into adjacent nipple and breast tissue. They have been confused with tubular carcinoma and low-grade adenosquamous carcinoma of the breast, both clinically and histologically. Complete excision is the therapy of choice, and only incompletely excised lesions have shown recurrence. We present this case to raise awareness that syringomatous adenoma of the nipple may present in patients with a simultaneous invasive carcinoma of the breast.
摘要：
乳头的汗管瘤腺瘤是一种罕见的良性浸润性肿瘤，于1983年首次被描述。在撰写本文时，一项文献检索显示，没有一例与乳腺浸润性癌相关的乳头汗管瘤。我们报告了一例40岁女性的乳头汗瘤状腺瘤，该女性还患有双侧浸润性导管癌和乳腺原位癌。据推测，乳头的汗瘤腺瘤起源于乳头的内分泌结构，因为它们与其他内分泌起源的肿瘤在微观上相似。如汗管瘤癌。然而,他们的确切来源是不确定的。尽管他们的行为是良性的，它们通常表现为向邻近的乳头和乳房组织的浸润性和扩张性增殖。他们被混淆为管状癌和低度乳腺腺鳞癌，临床和组织学。完全切除是首选疗法,只有未完全切除的病灶才有复发.我们提出这种情况是为了提高人们的认识，即同时患有乳腺浸润性癌的患者可能会出现乳头的汗管瘤状腺瘤。
