关键词: AF, atrial fibrillation BMV, balloon mitral valvotomy CMC, closed mitral commissurotomy LA, left atrium LAP, left atrial pressure LVEF, Left ventricular ejection fraction LVSD, Left ventricle systolic dysfunction MI, Myocardial Infarction MS, mitral stenosis MVA, mitral valve area MVR, mitral valve replacement Mitral regurgitation Mitral stenosis Mitral valve area NSR, normal sinus rhythm NYHA, New York Heart Association Nepal OMC, open mitral commissurotomy Outcomes PA, pulmonary artery PASP, pulmonary artery systolic pressure PTMC PTMC, percutaneous transvenous mitral commissurotomy RHD, rheumatic heart disease TTE TEE, Transthoracic Echocardiography Transesophageal Echo

来  源:   DOI:10.1016/j.amsu.2022.104867   PDF(Pubmed)

Abstract:
UNASSIGNED: Rheumatic heart disease (RHD), is a common cause of mitral stenosis (MS) in developing nations. As per current recommendation, Percutaneous Transvenous Mitral Commissurotomy (PTMC) is advised as a Class IA (I-Class Of Recommendation, COR; A-Level Of Evidence, LOE) indication in patients with symptomatic severe mitral stenosis. We aim to examine the clinical profile and in-hospital results of PTMC for mitral stenosis.
UNASSIGNED: A cross-sectional retrospective study was conducted at Manmohan Cardiothoracic Vascular and Transplant Center from April 2020 to May 2022. A structured questionnaire was used to collect the data and ethical approval for conducting the study was taken from the Institutional Review Committee (IRC) of Institute of Medicine (IOM). The data was collected in Microsoft Excel (Ver. 2013). For statistical analysis, SPSS 21 (IBM Corp. Released 2012. IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.) Association was measured using a parametric and non-parametric test (depending upon the distribution of data) and p value < 0.05 was considered significant.
UNASSIGNED: A total of 104 patients who met the inclusion criteria underwent PTMC during the study period. The mean age group of the patient was 41.7 ± 12.5 years, of which 23 (22.1%) were males and 81 (78.9%) were females. Mean mitral valve area prior to PTMC was 0.98 ± 0.19 mm2 that increased to 1.69 ± 0.19 mm2 after the procedure and it was statistically significant (p=<0.001). The post PTMC MVA varied with PTMC Wilkin\'s score with less than or equal to 8 having favorable outcomes.
UNASSIGNED: Successful PTMC is highly influenced by the patients\' increasing age, valve morphology (calcification, thickness, mobility), Left atrial dimensions, Pre PTMC mitral valve area, Degree of Baseline mitral regurgitation. Post procedure development of MR is usually well tolerated but rarely be severe enough requiring surgical valve replacement.
摘要:
未经批准:风湿性心脏病(RHD),是发展中国家二尖瓣狭窄(MS)的常见原因。根据目前的建议,建议将经皮经静脉二尖瓣切开术(PTMC)作为IA类(I类建议,COR;A级证据,有症状的重度二尖瓣狭窄患者的LOE)适应症。我们旨在检查PTMC治疗二尖瓣狭窄的临床特征和住院结果。
UNASSIGNED:于2020年4月至2022年5月在Manmohan心胸血管和移植中心进行了一项横断面回顾性研究。使用结构化问卷收集数据,并从医学研究所(IOM)的机构审查委员会(IRC)获得进行研究的伦理批准。数据在MicrosoftExcel中收集(Ver。2013).为了进行统计分析,SPSS21(IBM公司2012年发布IBMSPSSStatisticsforWindows,版本21.0。Armonk,纽约:IBM公司)使用参数和非参数检验(取决于数据的分布)来测量关联,并且p值<0.05被认为是显着的。
未经证实:在研究期间,共有104名符合纳入标准的患者接受了PTMC。患者的平均年龄为41.7±12.5岁,其中男性23人(22.1%),女性81人(78.9%)。PTMC前的平均二尖瓣面积为0.98±0.19mm2,手术后增加至1.69±0.19mm2,具有统计学意义(p=<0.001)。PTMC后MVA随PTMCWilkin的得分而变化,小于或等于8分,结果良好。
未经证实:成功的PTMC受患者年龄增长的影响很大,瓣膜形态(钙化,厚度,移动性),左心房尺寸,PTMC前二尖瓣面积,基线二尖瓣反流程度。MR的术后发展通常具有良好的耐受性,但很少足够严重,需要进行手术瓣膜置换。
公众号