Mesh : Humans Kidney Transplantation / adverse effects Treatment Outcome Tissue Donors Kidney / surgery physiology pathology Cold Ischemia / adverse effects Graft Survival

来  源:   DOI:10.6002/ect.2022.0064

Abstract:
In recent years, dual-kidney transplant has become an established method to overcome the inferior quality of donor organs and to allow the recovery of discarded human kidneys. However, in some cases, 1 of the 2 donor kidneys is unsuitable for transplant because of severe pathological changes, and the remaining marginal kidney is often discarded regardless of whether it meets criteria for dual-kidney transplant. Here, we report the use of marginal kidneys from 2 different donors, both of whom had missed kidney donation as a result of the serious pathological changes in their contralateral kidney. We combined the 2 donors\' marginal kidneys for dual-kidney transplant, which were implanted into the right iliac fossa of the recipient after cold ischemia times of 13 hours 40 minutes and 30 hours 30 minutes, respectively. The recipient had fully recovered and showed favorable renal function without complications at discharge and at the 1.5-year follow-up. To the best of our knowledge, this is the first case report of successful unilateral dual-kidney transplant of discarded kidneys from 2 expanded criteria donors.
摘要:
近年来,双肾脏移植已成为克服供体器官质量低劣并恢复被丢弃的人类肾脏的既定方法。然而,在某些情况下,由于严重的病理变化,2个供体肾脏中有1个不适合移植,剩余的边缘肾脏通常被丢弃,无论它是否符合双肾脏移植的标准。这里,我们报告了来自两个不同供体的边缘肾脏的使用,由于对侧肾脏的严重病理变化,两人都错过了肾脏捐赠。我们结合了两个供体的边缘肾脏进行双肾脏移植,在冷缺血时间为13小时40分钟和30小时30分钟后植入受体的右髂窝,分别。受者已完全康复,并在出院和1.5年随访时表现出良好的肾功能,无并发症。据我们所知,这是首例2例扩大标准供体废弃肾脏成功进行单侧双肾脏移植的病例报告.
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