A unique case of very low-dose subcutaneous ketamine use: Maintenance option of ketamine for treatment-resistant depression.

极低剂量皮下氯胺酮使用的独特案例 ： 氯胺酮治疗难治性抑郁症的维持选择。

• 发表时间: Dec 2022
• 来源期刊: Clin Case Rep
• DOI: 10.1002/ccr3.6675
• PMID: 36523376
• 文章类型: Case Reports
• 作者列表: Can AT,Hermens DF,Lagopoulos J

关键词: MADRS; NMDA; depression; ketamine; suicidality; treatment‐resistant

Abstract

Numerous studies have demonstrated that low-dose subanesthetic intravenous ketamine infusion treatment leads to rapid improvement of treatment-resistant depression. The following case report describes the use of a very low-dose subcutaneous ketamine as a form of maintenance in a patient with severe treatment-resistant depression using a retrospective chart review.

摘要

大量研究表明，低剂量亚麻醉药静脉输注氯胺酮治疗可快速改善难治性抑郁症。以下病例报告使用回顾性图表回顾，描述了使用极低剂量皮下氯胺酮作为严重难治性抑郁症患者的维持形式。