PDF(Pubmed)
Abstract：
Tuberculosis is a real public health problem in developing countries. The aim of our article was to study the epidemiological, clinical, diagnostic characteristics of female genital tuberculosis in Togo. This was a descriptive and cross-sectional study on all cases concerning histologically diagnosed female genital tuberculosis in the department of pathological anatomy of Lomé in 1997-2018 (20 years). We collected 22 cases of women\'s Genital tuberculosis (GT), representing 2.2% (1008 cases) of extra-pulmonary tuberculosis. The mean age of the patients was 33.8 ± 0.2 years. Nine (9) patients had a history of treated GT. Depending on the location, the ovaries and fallopian tubes were the most affected (n=9 cases, 40.9%). Eighteen patients (81.8%) had at least one immunosuppression factor including HIV in 13 patients (72.2%). The reasons for consultation were metrorrhagia and pelvic pain with an associated mass in 7 women discovered on clinical examination and imaging. The macroscopic appearance of the specimens was suggestive of the diagnosis of genital tuberculosis in 12 cases (54.5%). Histology revealed caseous necrosis isolated in 3 patients (13.6%) and associated with gigantocellular epithelioid granulomas in 19 patients (86.4%). The patients received standard antibiotic treatment combining rifampicin, isoniazid, ethambutol and pyrazinamide. Genital tuberculosis is a rare extra-pulmonary location in Togo, often occurring in women with HIV, and the clinical polymorphism can lead to confusion with gynecological cancers.
摘要：
结核病在发展中国家是一个真正的公共卫生问题。我们文章的目的是研究流行病学，临床,多哥女性生殖器结核的诊断特点.这是一项关于1997-2018年洛美病理解剖部门（20年）组织学诊断的女性生殖器结核的所有病例的描述性和横断面研究。我们收集了22例女性生殖器结核（GT），占2.2%(1008例)的肺外结核。患者的平均年龄为33.8±0.2岁。九(9)名患者有治疗的GT病史。根据位置,卵巢和输卵管受影响最大(n=9例，40.9%）。18例患者（81.8%）有至少一种免疫抑制因子，包括13例患者（72.2%）的HIV。咨询的原因是在临床检查和影像学检查中发现的7名妇女出血和盆腔疼痛以及相关肿块。标本的宏观外观提示12例（54.5％）诊断为生殖器结核。组织学显示3例（13.6％）分离出干酪样坏死，19例（86.4％）与大细胞上皮样肉芽肿有关。患者接受标准抗生素联合利福平治疗，异烟肼,乙胺丁醇和吡嗪酰胺。生殖器结核是多哥罕见的肺外部位,经常发生在感染艾滋病毒的女性身上，和临床多态性可能导致与妇科癌症混淆。
