Abstract：
Growth chart is a valuable clinical tool to monitor the growth and nutritional status of children. A growth chart widely used in China is based on the merged data sets of national surveys in 2005. We aimed to establish an up-to-date, complete growth curve for urban Chinese children and adolescents with a full range of ages.
Using data collected in a large-scale, cross-sectional study (Prevalence and Risk factors for Obesity and Diabetes in Youth (PRODY), 2017-2019), we analyzed 201,098 urban children aged 3 to 18 years from 11 provinces, autonomous regions, and municipalities that are geographically representative of China. All participants underwent physical examinations. Sex-specific percentiles of height-for-age and weight-for-age were constructed by Generalized Additive Models for Location Scale and Shape (GAMLSS) model. We also compared the median values of height-for-age or weight-for-age between our growth chart and the established growth reference using Welch-Satterthwaite T-Test.
Consistent with the established growth reference, we observed that the P50 percentile of height-for-age reached plateaus at the age of 15 years (172 cm) and 14 years (160 cm) for boys and girls, respectively. In addition, boys aged 10 ~ 14 years and girls aged 10 ~ 12 years exhibited the most dramatic weight difference compared to those of other age groups (19.5 kg and 10.3 kg, respectively). However, our growth chart had higher median values of weight-for-age and height-for-age than the established growth reference with mean increases in weight-for-age of 1.36 kg and 1.17 kg for boys and girls, respectively, and in height-for-age of 2.9 cm and 2.6 cm for boys and girls, respectively.
Our updated growth chart can serve as a reliable reference to assess the growth and nutritional status in urban Chinese children throughout the entire childhood.
Using data collected in a large-scale, cross-sectional study (Prevalence and Risk factors for Obesity and Diabetes in Youth (PRODY), 2017-2019), we analyzed 201,098 urban children aged 3 to 18 years from 11 provinces, autonomous regions, and municipalities that are geographically representative of China. All participants underwent physical examinations. Sex-specific percentiles of height-for-age and weight-for-age were constructed by Generalized Additive Models for Location Scale and Shape (GAMLSS) model. We also compared the median values of height-for-age or weight-for-age between our growth chart and the established growth reference using Welch-Satterthwaite T-Test.
Consistent with the established growth reference, we observed that the P50 percentile of height-for-age reached plateaus at the age of 15 years (172 cm) and 14 years (160 cm) for boys and girls, respectively. In addition, boys aged 10 ~ 14 years and girls aged 10 ~ 12 years exhibited the most dramatic weight difference compared to those of other age groups (19.5 kg and 10.3 kg, respectively). However, our growth chart had higher median values of weight-for-age and height-for-age than the established growth reference with mean increases in weight-for-age of 1.36 kg and 1.17 kg for boys and girls, respectively, and in height-for-age of 2.9 cm and 2.6 cm for boys and girls, respectively.
Our updated growth chart can serve as a reliable reference to assess the growth and nutritional status in urban Chinese children throughout the entire childhood.
摘要：
背景：生长图是监测儿童生长和营养状况的有价值的临床工具。在中国广泛使用的增长图基于2005年国家调查的合并数据集。我们的目标是建立一个最新的，中国城市儿童和青少年的完整生长曲线。
方法：使用大规模收集的数据，横断面研究(青年肥胖和糖尿病的患病率和危险因素(PRODY)，2017-2019),我们分析了来自11个省的201098名3至18岁的城市儿童，自治区,以及在地理上代表中国的直辖市。所有参与者都接受了体检。通过位置比例和形状的广义加性模型（GAMLSS）模型构建了年龄身高和年龄体重的性别特异性百分位数。我们还使用Welch-SatterthwaiteT检验比较了我们的生长图和已建立的生长参考之间的年龄身高或年龄体重的中值。
结果：与既定的增长参考一致，我们观察到，男孩和女孩的P50百分位身高在15岁（172厘米）和14岁（160厘米）时达到了高原，分别。此外,与其他年龄组相比，10~14岁的男孩和10~12岁的女孩表现出最显著的体重差异(19.5公斤和10.3公斤，分别)。然而,我们的增长图的年龄体重和年龄身高的中位数高于既定的增长参考值，男孩和女孩的年龄体重平均增加1.36公斤和1.17公斤，分别,男女身高分别为2.9厘米和2.6厘米，分别。
结论：我们更新的生长图可以作为评估中国城市儿童整个童年的生长和营养状况的可靠参考。
方法：使用大规模收集的数据，横断面研究(青年肥胖和糖尿病的患病率和危险因素(PRODY)，2017-2019),我们分析了来自11个省的201098名3至18岁的城市儿童，自治区,以及在地理上代表中国的直辖市。所有参与者都接受了体检。通过位置比例和形状的广义加性模型（GAMLSS）模型构建了年龄身高和年龄体重的性别特异性百分位数。我们还使用Welch-SatterthwaiteT检验比较了我们的生长图和已建立的生长参考之间的年龄身高或年龄体重的中值。
结果：与既定的增长参考一致，我们观察到，男孩和女孩的P50百分位身高在15岁（172厘米）和14岁（160厘米）时达到了高原，分别。此外,与其他年龄组相比，10~14岁的男孩和10~12岁的女孩表现出最显著的体重差异(19.5公斤和10.3公斤，分别)。然而,我们的增长图的年龄体重和年龄身高的中位数高于既定的增长参考值，男孩和女孩的年龄体重平均增加1.36公斤和1.17公斤，分别,男女身高分别为2.9厘米和2.6厘米，分别。
结论：我们更新的生长图可以作为评估中国城市儿童整个童年的生长和营养状况的可靠参考。
