PDF(Pubmed)
Abstract：
Pediatric-type follicular lymphoma is an uncommon and newly recognized entity of lymphoid neoplasm commonly encountered in the young population. Despite its indolent clinical course and localized nodal involvement, it has been characterized by its high-grade histopathological features. The overlapping features between this disease and several entities have made approaching this unique entity significantly challenging, with all such features being reflected in the strict diagnostic criteria highlighted by the WHO 2016 lymphoid malignancy classification. Despite its characteristic high-grade histology, its cure rates have remained high, with relapse and transformation rarely occurring. Interestingly, several cases have achieved remission following nodal disease resection, possibly eliminating the need for chemotherapy and radiation and preventing long-term morbidities from later approaches in disease survivors.
摘要：
小儿型滤泡性淋巴瘤是年轻人群中常见的一种罕见且新近被认识的淋巴肿瘤。尽管其临床过程缓慢且局部淋巴结受累，它的特点是其高级组织病理学特征。这种疾病和几个实体之间的重叠特征使得接近这个独特的实体具有极大的挑战性，所有这些特征都反映在WHO2016年淋巴恶性肿瘤分类所强调的严格诊断标准中.尽管它具有很高的组织学特征，它的治愈率仍然很高，复发和转化很少发生。有趣的是,结节性疾病切除术后，有几例病例已经缓解，可能消除对化疗和放疗的需要，并防止疾病幸存者后期治疗的长期发病率。
