PDF(Pubmed)
Abstract：
UNASSIGNED: Endometrial stromal sarcoma is a relatively rare malignant tumor that derives from the malignant transformation of primitive uterine mesenchymal cells. It can lead to distant metastases. High-grade endometrial stromal sarcoma is extremely rare. The adrenal glands are an unreported site of metastasis.
UNASSIGNED: A 71-year-old woman with a diagnosis of endometrial stromal sarcoma 30 months ago. After receiving treatment with radiotherapy and chemotherapy, the patient was kept asymptomatic during the follow-up until 2 years later, when she complained of dyspnea. Pulmonary and right adrenal gland metastases were detected by 18F-FDG PET/CT. The right upper lobe mass was diagnosed as a high-grade endometrial stromal sarcoma metastasis after postoperative pathology. Due to the patient\'s high risk of surgery, as she had many underlying diseases, we performed adequate preoperative preparation. The physical examination revealed that a hard mass was palpable in the right renal area. The right adrenal mass was resected in our hospital. Immunohistochemistry showed ER (-), PR (-), CD10 (+), P16 (+), Ki-67 (50%). The final diagnosis on pathological examination was a high-grade ESS metastatic to the right adrenal gland. The patient continued treatment in other hospitals after surgical resection. After four months of postoperative follow-up, metastasis was detected again during a PET/CT examination at an outside hospital.
UNASSIGNED: Endometrial stromal sarcoma is rare, and the adrenal glands are an unreported site of metastasis. It has no specific clinical symptoms and mainly found for other reasons. The diagnosis still depends on pathology and immunohistochemistry. If there is no relevant past history, it is difficult to exclude a primary adrenal tumor.
UNASSIGNED: A 71-year-old woman with a diagnosis of endometrial stromal sarcoma 30 months ago. After receiving treatment with radiotherapy and chemotherapy, the patient was kept asymptomatic during the follow-up until 2 years later, when she complained of dyspnea. Pulmonary and right adrenal gland metastases were detected by 18F-FDG PET/CT. The right upper lobe mass was diagnosed as a high-grade endometrial stromal sarcoma metastasis after postoperative pathology. Due to the patient\'s high risk of surgery, as she had many underlying diseases, we performed adequate preoperative preparation. The physical examination revealed that a hard mass was palpable in the right renal area. The right adrenal mass was resected in our hospital. Immunohistochemistry showed ER (-), PR (-), CD10 (+), P16 (+), Ki-67 (50%). The final diagnosis on pathological examination was a high-grade ESS metastatic to the right adrenal gland. The patient continued treatment in other hospitals after surgical resection. After four months of postoperative follow-up, metastasis was detected again during a PET/CT examination at an outside hospital.
UNASSIGNED: Endometrial stromal sarcoma is rare, and the adrenal glands are an unreported site of metastasis. It has no specific clinical symptoms and mainly found for other reasons. The diagnosis still depends on pathology and immunohistochemistry. If there is no relevant past history, it is difficult to exclude a primary adrenal tumor.
摘要：
未经证实：子宫内膜间质肉瘤是一种相对罕见的恶性肿瘤，源于原始子宫间充质细胞的恶性转化。它可以导致远处转移。高级别子宫内膜间质肉瘤极为罕见。肾上腺是未报告的转移部位。
未经证实：一名71岁女性，30个月前诊断为子宫内膜间质肉瘤。接受放疗和化疗后，患者在随访期间一直无症状，直到2年后，当她抱怨呼吸困难时。18F-FDGPET/CT检查肺和右肾上腺转移。右上叶肿块经术后病理诊断为高级别子宫内膜间质肉瘤转移。由于病人的手术风险很高,因为她有许多潜在的疾病，我们进行了充分的术前准备.体格检查显示右肾区域可触及硬块。我们医院切除了右肾上腺肿块。免疫组织化学显示ER(-),PR(-),CD10(+),P16(+),Ki-67（50%）。病理检查的最终诊断是右侧肾上腺的高度ESS转移。患者在手术切除后继续在其他医院治疗。术后4个月随访,在医院外的PET/CT检查中再次检测到转移.
未经证实：子宫内膜间质肉瘤罕见，肾上腺是未报告的转移部位。无特异性临床症状，主要为其他原因。诊断仍取决于病理和免疫组织化学。如果没有相关的过去历史，很难排除原发性肾上腺肿瘤。
未经证实：一名71岁女性，30个月前诊断为子宫内膜间质肉瘤。接受放疗和化疗后，患者在随访期间一直无症状，直到2年后，当她抱怨呼吸困难时。18F-FDGPET/CT检查肺和右肾上腺转移。右上叶肿块经术后病理诊断为高级别子宫内膜间质肉瘤转移。由于病人的手术风险很高,因为她有许多潜在的疾病，我们进行了充分的术前准备.体格检查显示右肾区域可触及硬块。我们医院切除了右肾上腺肿块。免疫组织化学显示ER(-),PR(-),CD10(+),P16(+),Ki-67（50%）。病理检查的最终诊断是右侧肾上腺的高度ESS转移。患者在手术切除后继续在其他医院治疗。术后4个月随访,在医院外的PET/CT检查中再次检测到转移.
未经证实：子宫内膜间质肉瘤罕见，肾上腺是未报告的转移部位。无特异性临床症状，主要为其他原因。诊断仍取决于病理和免疫组织化学。如果没有相关的过去历史，很难排除原发性肾上腺肿瘤。
