关键词: Antibiotic susceptibility bacterial resistance multidrug-resistant puerperal sepsis

来  源:   DOI:10.4103/jfmpc.jfmpc_2419_21   PDF(Pubmed)

Abstract:
UNASSIGNED: Due to the lack of resources for culture and antibiotic susceptibility testing in most underdeveloped countries, puerperal sepsis is treated empirically with a wide range of antibiotics. Empirical treatment, on the other hand, does not ensure treatment effectiveness and may even contribute to antibiotic resistance. So, we studied cases of puerperal sepsis, its socio-demographic factors, bacterial isolates, and antibiotic sensitivity in a tertiary health center.
UNASSIGNED: This was a cross-sectional study conducted at the obstetrics and gynecology department of a tertiary health center in India from April 2019 to September 2020. During this time, all patients with sepsis who met the criteria for inclusion were included. After granting an informed written consent, the subjects were registered on a pre-designed proforma.
UNASSIGNED: There were 2,049 obstetrical admissions throughout this period, with 106 (5.1%) of these having puerperal sepsis. The majority of these women (58.7%) were between the ages of 21 and 30, were multiparous (96.5%), and unbooked. Fever 104 (98.1%) was the most prevalent clinical characteristic, whereas wound gape was the most common consequence (47.1%). Klebsiella aerogens was the most common organism found in various cultures. Many organisms were shown to be multidrug-resistant and sensitive to gentamycin and amikacin.
UNASSIGNED: Klebsiella aerogens wasthe most common cause of puerperal sepsis in this investigation. Because the causal agents of puerperal sepsis and their antibiotic sensitivity patterns change over time, positive blood culture and antibiotic susceptibility of the isolates are the best guides for selecting the optimum antimicrobial therapy for treating sepsis.
摘要:
UNASSIGNED:由于大多数不发达国家缺乏用于培养和抗生素敏感性测试的资源,产褥期败血症的治疗经验广泛的抗生素。经验治疗,另一方面,不能确保治疗效果,甚至可能导致抗生素耐药性。所以,我们研究了产褥期败血症的病例,它的社会人口因素,细菌分离物,三级卫生中心的抗生素敏感性。
UNASSIGNED:这是一项横断面研究,于2019年4月至2020年9月在印度三级卫生中心的妇产科部门进行。在此期间,所有符合入选标准的脓毒症患者均被纳入.在给予知情的书面同意后,受试者在预先设计的形式上注册。
未经评估:在此期间有2,049例产科入院,其中106例(5.1%)患有产褥期败血症。这些妇女中的大多数(58.7%)年龄在21至30岁之间,是多胎(96.5%),和未预订。发热104(98.1%)是最普遍的临床特征,而伤口裂开是最常见的结果(47.1%)。产气克雷伯菌是各种培养物中最常见的生物。许多生物被证明具有多重耐药性,并且对庆大霉素和阿米卡星敏感。
未经证实:产气克雷伯菌是本次调查中产褥期败血症的最常见原因。因为产褥期败血症的病因及其抗生素敏感性模式随着时间的推移而变化,血培养阳性和分离株的抗生素敏感性是选择治疗脓毒症的最佳抗菌疗法的最佳指南。
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