关键词: blood-brain barrier cerebrovascular abnormalities contrast-induced encephalopathy hypothyroidism percutaneous coronary intervention

来  源:   DOI:10.3389/fcvm.2022.957779   PDF(Pubmed)

Abstract:
UNASSIGNED: Contrast-induced encephalopathy (CIE) is a complication associated with the administration of iodinated contrast, which usually happens minutes to hours after contact with contrast, and fully recovers within 72 h. The clinical manifestations of CIE are diverse, and the pathological mechanism is not explicit.
UNASSIGNED: We report the case of a 66-year-old female who suffered from a delayed CIE following the administration of iodinated contrast agent. Symptoms were severe. Imaging examination, biochemical and etiological detection were performed timely. The course of neurological symptoms was atypical. Her complex complications of hypothyroidism and cerebrovascular abnormalities contributed to more challenges, which were also clues to the diagnosis. With prompt and active treatment, the patient recovered fully over 10 days.
UNASSIGNED: The diagnosis standard of CIE highly depends on the association with the contact of contrast and the exclusion of other nervous system diseases. Complicated clinical circumstances and individual specificity can lead to different clinical manifestations of CIE, making it even more difficult to diagnose and treat. Prompt and dynamic imaging examination would provide great value in the diagnosis and evaluation of CIE. Timely diagnosis and intervention may be the key to its satisfying prognosis.
摘要:
未经证实:造影剂诱导性脑病(CIE)是与使用碘化造影剂相关的并发症,这通常发生在与造影剂接触后几分钟到几小时,并在72小时内完全恢复。CIE的临床表现多样,病理机制不明确。
未经评估:我们报告了一例66岁的女性,她在服用碘化造影剂后出现延迟CIE。症状很严重。影像学检查,及时进行生化和病原学检测。神经系统症状的过程是不典型的。她复杂的甲状腺功能减退和脑血管异常并发症带来了更多挑战,这也是诊断的线索。通过及时积极的治疗,患者在10天内完全康复。
非ASSIGNED:CIE的诊断标准高度依赖于与造影剂接触和排除其他神经系统疾病的关联。复杂的临床情况和个体特异性可导致CIE的不同临床表现,使得诊断和治疗更加困难。及时和动态的影像学检查将为CIE的诊断和评估提供巨大的价值。及时诊断和干预可能是其预后满意的关键。
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