Abstract：
OBJECTIVE: The aim of this systematic review was to examine the literature on aggressive and chronic periodontitis and orthodontics to clarify the therapy-relevant aspects of orthodontic treatment with altered biomechanics in periodontally compromised dentition.
METHODS: Literature searches were conducted in the electronic databases \"PubMed\" and \"DIMDI\" using the keywords \"aggressive periodontitis AND ortho*,\" \"aggressive periodontitis AND orthodontics,\" \"chronic periodontitis AND ortho*,\" and \"chronic periodontitis AND orthodontics\" for the publication period from January 1990 to July 2022. In addition, a manual search was carried out in the selected trade journals \"Community Dental Health,\" \"European Journal of Oral Sciences,\" and \"Parodontologie.\" Human clinical trials were included, whereas animal experimental studies, case reports, and reviews were generally excluded. The appropriate studies were selected, and the relevant data was tabulated according to different parameters, regarding the study design, the study structure, and the conduct of the study.
RESULTS: A total of 1067 articles were found in the preliminary electronic search. The manual search and review of all related bibliographies resulted in an additional 1591 hits. After the first screening, 43 articles were classified as potentially relevant and reviewed in their original form. After the suitability test, 5 studies with a total of 366 participants were included in the final evaluation. These included one randomized controlled trial and four low-evidence intervention studies. The studies were conducted in two university hospitals and three private practices. All participants underwent scaling and root plaining and periodontal surgery before the orthodontic treatment started. Mean probing pocket depth reduction before and after the interdisciplinary treatment was analyzed in all the included studies; mean difference in clinical attachment level in four of the studies was also included. All participants were enrolled in a continuous recall system. In all studies, orthodontic therapy in periodontally compromised patients improved function and esthetics, resulting in lower probing depths and clinical attachment gains.
CONCLUSIONS: Orthodontic treatment can be used for patients with reduced periodontal support to stabilize clinical findings and improve function and esthetics. The prerequisite for this is a profound knowledge of altered biomechanics and an adapted interdisciplinary treatment approach. Due to the large heterogeneity of the included studies and their limited methodological quality, the results obtained in this review must be considered critically. Further randomized controlled long-term studies with comparable study designs are necessary to obtain reliable and reproducible treatment results.
CONCLUSIONS: Patients with periodontal impairment can be successfully treated with orthodontics as part of interdisciplinary therapy. Orthodontic treatment has no negative impact on the periodontium; if minimal, controlled forces are used under non-inflammatory conditions.
METHODS: Literature searches were conducted in the electronic databases \"PubMed\" and \"DIMDI\" using the keywords \"aggressive periodontitis AND ortho*,\" \"aggressive periodontitis AND orthodontics,\" \"chronic periodontitis AND ortho*,\" and \"chronic periodontitis AND orthodontics\" for the publication period from January 1990 to July 2022. In addition, a manual search was carried out in the selected trade journals \"Community Dental Health,\" \"European Journal of Oral Sciences,\" and \"Parodontologie.\" Human clinical trials were included, whereas animal experimental studies, case reports, and reviews were generally excluded. The appropriate studies were selected, and the relevant data was tabulated according to different parameters, regarding the study design, the study structure, and the conduct of the study.
RESULTS: A total of 1067 articles were found in the preliminary electronic search. The manual search and review of all related bibliographies resulted in an additional 1591 hits. After the first screening, 43 articles were classified as potentially relevant and reviewed in their original form. After the suitability test, 5 studies with a total of 366 participants were included in the final evaluation. These included one randomized controlled trial and four low-evidence intervention studies. The studies were conducted in two university hospitals and three private practices. All participants underwent scaling and root plaining and periodontal surgery before the orthodontic treatment started. Mean probing pocket depth reduction before and after the interdisciplinary treatment was analyzed in all the included studies; mean difference in clinical attachment level in four of the studies was also included. All participants were enrolled in a continuous recall system. In all studies, orthodontic therapy in periodontally compromised patients improved function and esthetics, resulting in lower probing depths and clinical attachment gains.
CONCLUSIONS: Orthodontic treatment can be used for patients with reduced periodontal support to stabilize clinical findings and improve function and esthetics. The prerequisite for this is a profound knowledge of altered biomechanics and an adapted interdisciplinary treatment approach. Due to the large heterogeneity of the included studies and their limited methodological quality, the results obtained in this review must be considered critically. Further randomized controlled long-term studies with comparable study designs are necessary to obtain reliable and reproducible treatment results.
CONCLUSIONS: Patients with periodontal impairment can be successfully treated with orthodontics as part of interdisciplinary therapy. Orthodontic treatment has no negative impact on the periodontium; if minimal, controlled forces are used under non-inflammatory conditions.
摘要：
目的：本系统综述的目的是研究有关侵袭性和慢性牙周炎和正畸的文献，以阐明正畸治疗与牙周受损牙列生物力学改变的治疗相关方面。
方法：在电子数据库\"PubMed\"和\"DIMDI\"中使用关键词\"侵袭性牙周炎和矫正*进行文献检索，“”侵袭性牙周炎和正畸，“”慢性牙周炎和矫正*，“和“慢性牙周炎和正畸学”，出版期为1990年1月至2022年7月。此外,在选定的行业期刊“社区牙科健康，“”欧洲口腔科学杂志，\"和\"牙本质。“包括人体临床试验，而动物实验研究，病例报告,和评论通常被排除在外。选择了适当的研究，并根据不同的参数对相关数据进行制表，关于研究设计，研究结构，以及研究的进行。
结果：初步电子检索共发现1067篇文章。对所有相关参考书目的手动搜索和审查导致了额外的1591次点击。第一次筛选后,43篇文章被归类为潜在相关的，并以其原始形式进行了审查。适用性试验后,最终评估包括5项研究，共366名参与者。其中包括一项随机对照试验和四项低证据干预研究。这些研究是在两家大学医院和三家私人诊所进行的。在正畸治疗开始之前，所有参与者都接受了刮削和牙根平整和牙周手术。在所有纳入的研究中，分析了跨学科治疗前后的平均探查袋深度减少；还包括了其中四项研究中临床依恋水平的平均差异。所有参与者都加入了连续召回系统。在所有研究中,正畸治疗牙周病患者改善功能和美学，导致较低的探测深度和临床依恋增益。
结论：正畸治疗可用于牙周支持减少的患者，以稳定临床发现，改善功能和美学。这样做的先决条件是对改变的生物力学和适应的跨学科治疗方法的深刻了解。由于纳入研究的异质性大，方法学质量有限，必须严格考虑本综述中获得的结果.需要进一步的随机对照长期研究和可比的研究设计，以获得可靠和可重复的治疗结果。
结论：作为跨学科治疗的一部分，正畸可以成功治疗牙周病患者。正畸治疗对牙周组织没有负面影响;如果最小，在非炎症条件下使用控制力。
方法：在电子数据库\"PubMed\"和\"DIMDI\"中使用关键词\"侵袭性牙周炎和矫正*进行文献检索，“”侵袭性牙周炎和正畸，“”慢性牙周炎和矫正*，“和“慢性牙周炎和正畸学”，出版期为1990年1月至2022年7月。此外,在选定的行业期刊“社区牙科健康，“”欧洲口腔科学杂志，\"和\"牙本质。“包括人体临床试验，而动物实验研究，病例报告,和评论通常被排除在外。选择了适当的研究，并根据不同的参数对相关数据进行制表，关于研究设计，研究结构，以及研究的进行。
结果：初步电子检索共发现1067篇文章。对所有相关参考书目的手动搜索和审查导致了额外的1591次点击。第一次筛选后,43篇文章被归类为潜在相关的，并以其原始形式进行了审查。适用性试验后,最终评估包括5项研究，共366名参与者。其中包括一项随机对照试验和四项低证据干预研究。这些研究是在两家大学医院和三家私人诊所进行的。在正畸治疗开始之前，所有参与者都接受了刮削和牙根平整和牙周手术。在所有纳入的研究中，分析了跨学科治疗前后的平均探查袋深度减少；还包括了其中四项研究中临床依恋水平的平均差异。所有参与者都加入了连续召回系统。在所有研究中,正畸治疗牙周病患者改善功能和美学，导致较低的探测深度和临床依恋增益。
结论：正畸治疗可用于牙周支持减少的患者，以稳定临床发现，改善功能和美学。这样做的先决条件是对改变的生物力学和适应的跨学科治疗方法的深刻了解。由于纳入研究的异质性大，方法学质量有限，必须严格考虑本综述中获得的结果.需要进一步的随机对照长期研究和可比的研究设计，以获得可靠和可重复的治疗结果。
结论：作为跨学科治疗的一部分，正畸可以成功治疗牙周病患者。正畸治疗对牙周组织没有负面影响;如果最小，在非炎症条件下使用控制力。
