关键词: anticancer dietary compounds ayanin isorhamnetin laricitrin pharmacological effect syringetin

Mesh : Flavonols / pharmacology chemistry Antioxidants / pharmacology Glycosides / pharmacology

来  源:   DOI:10.3390/nu14235157

Abstract:
Mono- and poly-O-methylated flavonols and their glycoside derivatives belong to the group of natural plant polyphenols with a wide spectrum of pharmacological activities. These compounds are known for their antioxidant, antimutagenic, hepatoprotective, antidiabetic, and antilipogenic properties. Additionally, they inhibit carcinogenesis and cancer development. Having in mind the multidirectional biological activity of methylated flavonols, we would like to support further study on their health-promoting activities; in this review we summarized the most recent reports on syringetin and some of its structural analogues: laricitrin, ayanin, and isorhamnetin. Natural sources and biological potential of these substances were described based on the latest research papers.
摘要:
单-和多-O-甲基化黄酮醇及其糖苷衍生物属于具有广泛药理活性的天然植物多酚。这些化合物以其抗氧化剂而闻名,抗突变,保肝,抗糖尿病药,和抗脂肪生成特性。此外,它们抑制致癌作用和癌症发展。考虑到甲基化黄酮醇的多向生物活性,我们希望支持对其促进健康活动的进一步研究;在这篇综述中,我们总结了关于丁香素及其一些结构类似物的最新报告:laricitrin,ayanin,和isorhametin.根据最新的研究论文描述了这些物质的天然来源和生物潜力。
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