Abstract：
It is unclear how the COVID-19 pandemic impacted human papillomavirus (HPV) vaccine uptake and which sociodemographic groups may have been most impacted. We aimed to assess differences in HPV vaccine uptake (initiation and completion) before and during the pandemic in the United States. We conducted a cross-sectional study using data from the 2019 to 2020 National Immunization Surveys - Teen (NIS-Teen), comparing vaccine initiation and completion rates in 2019 vs. 2020, based on confirmed reports by a healthcare provider. Weighted logistic regression analysis estimated odds of vaccine initiation and completion for both adolescent and parental characteristics. There were 18,788 adolescents in 2019 and 20,162 in 2020. There was 3.6% increase in HPV vaccine initiation (71.5% vs. 75.1%) and a 4.4% in completion (54.2% vs. 58.6%) rates from 2019 to 2020. In 2020, Non-Hispanic White teens were significantly less likely to initiate (aOR = 0.62, 95% CI: 0.49, 0.79) and complete (aOR = 0.71, 95% CI: 0.58, 0.86) vaccine uptake compared with non-Hispanic Black teens. Additionally, teens who lived above the poverty line were also less likely to initiate HPV vaccination (aOR = 0.63, 95% CI: 0.49, 0.80) or complete them (aOR = 0.73, 95% CI: 0.60, 0.90), compared to those who lived below the poverty line. During the COVID-19 pandemic in 2020, some historically advantaged socioeconomic groups such as those living above the poverty line were less likely to receive HPV vaccine. The impact of the pandemic on HPV vaccine uptake may transcend traditional access to care factors.
摘要：
目前尚不清楚COVID-19大流行如何影响人乳头瘤病毒（HPV）疫苗的摄取，以及哪些社会人口统计学群体可能受到的影响最大。我们旨在评估美国大流行之前和期间HPV疫苗摄取（开始和完成）的差异。我们使用2019年至2020年国家免疫调查的数据进行了一项横断面研究-青少年（NIS-青少年），比较2019年疫苗起始率和完成率与2020年，根据医疗保健提供者的确认报告。加权逻辑回归分析估计了青少年和父母特征的疫苗启动和完成几率。2019年有18,788名青少年，2020年有20,162名青少年。HPV疫苗接种增加了3.6%(71.5%vs.75.1%）和4.4%的完成率（54.2%与58.6%），2019年至2020年。2020年，与非西班牙裔黑人青少年相比，非西班牙裔白人青少年开始（aOR=0.62，95％CI：0.49，0.79）和完成（aOR=0.71，95％CI：0.58，0.86）疫苗摄取的可能性显着降低。此外,生活在贫困线以上的青少年也不太可能开始接种HPV疫苗（aOR=0.63，95％CI：0.49，0.80）或完成接种（aOR=0.73，95％CI：0.60，0.90），与生活在贫困线以下的人相比。在2020年COVID-19大流行期间，一些历史上处于优势地位的社会经济群体，如生活在贫困线以上的群体接种HPV疫苗的可能性较小。大流行对HPV疫苗摄取的影响可能超越传统的获得护理因素。
