关键词: COVID‐19 SARS‐CoV‐2 stress cardiomyopathy systematic review takotsubo cardiomyopathy takotsubo syndrome

来  源:   DOI:10.1002/hsr2.972   PDF(Pubmed)

Abstract:
UNASSIGNED: Takotsubo syndrome (TTS), also known as stress cardiomyopathy, is characterized by acute and transient left ventricular dysfunction and has increased during the COVID-19 pandemic. Herein, we aim to review studies on TTS that were associated with COVID-19 infection, vaccine, and other COVID-19-related etiologies including psychosocial stressors.
UNASSIGNED: We systematically searched PubMed, EMBASE, and Scopus up to May 12, 2022. We included case reports, case series, and original articles that reported at least one TTS case associated with COVID-19, or TTS cases after receiving COVID-19 vaccines, or TTS cases secondary to psychological stress due to the COVID-19 pandemic. The quality assessment was conducted using the Joanna Briggs Institute checklist.
UNASSIGNED: Sixty-seven articles including 102 cases were included. Hypertension was the most frequently accompanying comorbidity (N = 67 [65.6%]) and the mean left ventricular ejection fraction was 36.5%. Among COVID-19 patients, the in-hospital mortality rate was 33.3%. On the other hand, only one COVID-19-negative individual expired (2.3%). The most common presenting clinical symptom was dyspnea in 42 (73.6%) patients. the mean time interval from the first symptom to admission was 7.2 days. The most common chest imaging finding was ground-glass opacity which was reported in 14 (31.1%) participants. The most common abnormalities were T-wave inversion in 35 (43.2%) and ST-segment elevation in 30 (37%). Brain natriuretic peptide and troponin were elevated in 94.7% and 95.9% of participants, respectively.
UNASSIGNED: The TTS in patients with COVID-19 is almost rare, whereas it could lead to a great mortality and morbidity. An individual with COVID-19, especially an elderly woman, presented with dyspnea in addition to a rise in brain natriuretic peptide and troponin should be evaluated for TTS.
摘要:
未经证实:Takotsubo综合征(TTS),也被称为应激性心肌病,以急性和短暂性左心室功能障碍为特征,在COVID-19大流行期间有所增加。在这里,我们旨在回顾与COVID-19感染相关的TTS研究,疫苗,以及其他与COVID-19相关的病因,包括心理社会应激源。
未经授权:我们系统地搜索了PubMed,EMBASE,和Scopus至2022年5月12日。我们包括病例报告,案例系列,以及报告至少一例与COVID-19相关的TTS病例或接受COVID-19疫苗后的TTS病例的原始文章,或TTS病例继发于COVID-19大流行导致的心理压力。质量评估是使用JoannaBriggs研究所检查表进行的。
UNASSIGNED:共纳入67篇,包括102例。高血压是最常见的合并症(N=67[65.6%]),平均左心室射血分数为36.5%。在COVID-19患者中,住院死亡率为33.3%.另一方面,只有一名COVID-19阴性个体过期(2.3%)。42例(73.6%)患者最常见的临床症状是呼吸困难。从首次出现症状到入院的平均时间间隔为7.2天.最常见的胸部影像学发现是毛玻璃混浊,在14名(31.1%)参与者中报告。最常见的异常是35例(43.2%)的T波倒置和30例(37%)的ST段抬高。94.7%和95.9%的参与者脑钠肽和肌钙蛋白升高,分别。
未经证实:COVID-19患者的TTS几乎很少见,而它可能导致巨大的死亡率和发病率。患有COVID-19的人,尤其是老年妇女,除了脑钠肽和肌钙蛋白升高外,还应评估呼吸困难的TTS。
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