Abstract：
Patients with terminal illnesses have different symptoms. The goal of palliative care is to alleviate the suffering induced by these symptoms. Available research on symptoms has focused on their prevalence or identification of clusters. Little is known about the central symptoms contributing to the maintenance of the whole system of symptoms or the mechanism of influence between symptoms, particularly between physical and psychosocial symptoms.
The study used network analysis to explore symptom clusters among patients with terminal illnesses and identify the central symptoms, the bridge symptoms, and pathways between physical and psychosocial symptoms.
This is a retrospective cohort study using baseline symptom assessment of 677 adults with terminal illnesses receiving care from the Integrated Community End-of-Life Care Support Teams.
Three symptom clusters were identified: physical, psychological, and practical clusters. \"Weakness or lack of energy\" was identified as the crucial symptom affecting the changes of other symptoms, followed by depression and anxiety. Three connections between the psychological and physical symptoms were identified: anxiety-pain, depression-constipation, and perceived family anxiety-poor appetite pathways. Pathways of practical concern-peace and practical concern-depression were indicated between practical and psychological symptoms.
This study is the first of its kind to investigate the connections and mechanism of influence between symptoms among patients with terminal illnesses. It offers clear pathways for intervention with the most influential symptoms of weakness, anxiety, and depression.
The study used network analysis to explore symptom clusters among patients with terminal illnesses and identify the central symptoms, the bridge symptoms, and pathways between physical and psychosocial symptoms.
This is a retrospective cohort study using baseline symptom assessment of 677 adults with terminal illnesses receiving care from the Integrated Community End-of-Life Care Support Teams.
Three symptom clusters were identified: physical, psychological, and practical clusters. \"Weakness or lack of energy\" was identified as the crucial symptom affecting the changes of other symptoms, followed by depression and anxiety. Three connections between the psychological and physical symptoms were identified: anxiety-pain, depression-constipation, and perceived family anxiety-poor appetite pathways. Pathways of practical concern-peace and practical concern-depression were indicated between practical and psychological symptoms.
This study is the first of its kind to investigate the connections and mechanism of influence between symptoms among patients with terminal illnesses. It offers clear pathways for intervention with the most influential symptoms of weakness, anxiety, and depression.
摘要：
未经证实：患有绝症的患者有不同的症状。姑息治疗的目的是减轻这些症状引起的痛苦。关于症状的现有研究集中在它们的患病率或簇的识别上。对有助于维持整个症状系统的中心症状或症状之间的影响机制知之甚少。特别是在身体和心理症状之间。
UNASSIGNED：该研究使用网络分析来探索绝症患者的症状群，并确定中心症状，桥的症状,以及生理和心理症状之间的通路。
UNASSIGNED：这是一项回顾性队列研究，使用基线症状评估对677名患有绝症的成年人进行了综合社区临终关怀支持小组的护理。
未经评估：确定了三个症状群：身体，心理,和实用的集群。“虚弱或缺乏能量”被确定为影响其他症状变化的关键症状，其次是抑郁和焦虑。确定了心理和生理症状之间的三种联系：焦虑-疼痛，抑郁症-便秘,和感知到的家庭焦虑-食欲差的途径。在实际症状和心理症状之间指出了实际关注和平和实际关注抑郁的途径。
UNASSIGNED：这项研究是首次调查绝症患者症状之间的联系和影响机制。它为最具影响力的虚弱症状提供了明确的干预途径，焦虑,和抑郁症。
UNASSIGNED：该研究使用网络分析来探索绝症患者的症状群，并确定中心症状，桥的症状,以及生理和心理症状之间的通路。
UNASSIGNED：这是一项回顾性队列研究，使用基线症状评估对677名患有绝症的成年人进行了综合社区临终关怀支持小组的护理。
未经评估：确定了三个症状群：身体，心理,和实用的集群。“虚弱或缺乏能量”被确定为影响其他症状变化的关键症状，其次是抑郁和焦虑。确定了心理和生理症状之间的三种联系：焦虑-疼痛，抑郁症-便秘,和感知到的家庭焦虑-食欲差的途径。在实际症状和心理症状之间指出了实际关注和平和实际关注抑郁的途径。
UNASSIGNED：这项研究是首次调查绝症患者症状之间的联系和影响机制。它为最具影响力的虚弱症状提供了明确的干预途径，焦虑,和抑郁症。
