Abstract：
Okara is a by-product of soymilk manufacturing and a rich source of protein and dietary fiber. This study investigates whether dietary soymilk-okara powder intake in the long term affects the body composition and gut microbiota flora in healthy Japanese adults. In total, 46 subjects (43 women) were enrolled. All subjects ingested 15 g of soymilk-okara powder every day for 12 weeks. Subjects\' body composition was assessed over four weeks. At baseline and after intervention for 12 weeks, fecal short-chain fatty acid concentrations and microbiota percentages were measured. The body muscle weight significantly increased, and the percentage of body fat significantly decreased at 4, 8, and 12 weeks after the intervention. The increase in body muscle after 12 weeks was 0.6 kg (interquartile range:-0.03 to 1.0). The decrease in body fat was -0.9% (interquartile range: -1.6 to -0.2). There was a significant negative correlation between the changes in body fat and body muscle. For the fecal percentages of Coriobacteriaceae, Lactobacillales, Bacteroides, Clostridium cluster IV, and Clostridium cluster XI, there were significant differences between the baseline and 12 weeks after the intervention. Furthermore, there were significant negative correlations between the changes in body fat percentage and fecal acetic acid and propionic acid levels. Therefore, a dietary intake of 15 g of soymilk-okara powder for 12 weeks induced a decrease in body fat, an increase in body muscle, and a change in fecal microbiota flora. Soymilk-okara powder is effective in improving body composition and changing the intestinal microbiota flora in healthy Japanese adults.
摘要：
Okara是豆浆制造的副产品，是蛋白质和膳食纤维的丰富来源。这项研究调查了长期摄入豆浆-豆渣粉是否会影响健康日本成年人的身体成分和肠道菌群。总的来说,纳入46名受试者(43名女性)。所有受试者每天摄入15g豆浆-豆渣粉,持续12周。在四周内评估受试者的身体组成。在基线和干预12周后，测量粪便短链脂肪酸浓度和微生物群百分比。身体肌肉重量显著增加，干预后第4、8和12周，体脂百分比显着下降。12周后身体肌肉的增加为0.6kg（四分位间距：-0.03至1.0）。体脂的减少为-0.9%(四分位间距:-1.6至-0.2)。体脂变化与体肌变化呈显著负相关。对于科氏杆菌科的粪便百分比，乳酸杆菌,拟杆菌,梭菌群IV,和梭状芽孢杆菌XI簇，基线和干预后12周之间存在显著差异.此外，体内脂肪百分比的变化与粪便乙酸和丙酸水平之间存在显着负相关。因此,饮食中摄入15克豆浆-豆渣粉12周导致体内脂肪减少，身体肌肉的增加，和粪便菌群的变化。豆浆-豆渣粉可有效改善健康日本成年人的身体成分并改变肠道菌群。
