关键词: Alzheimer brain disorder chronic disease nanomedicine nanotechnology

来  源:   DOI:10.3389/fbioe.2022.1042986   PDF(Pubmed)

Abstract:
The buildup of beta-amyloid plaques in the brain results in Alzheimer\'s disease (AD), a neurodegenerative condition. A permanent treatment for AD is not yet available. Only a slowing down of its advancement is possible with the current pharmaceutical options. Nevertheless, nanotechnology has proven to be advantageous in medical applications. It has a lot of potential for AD therapy, particularly in diagnosing the condition and providing an alternative course of treatment. In this review, we outline the developments and benefits of nanomedicines in treating AD. Prospective nanomedicines for diagnosing and surveillance therapeutic interventions for AD and other diseases of the central nervous system (CNS) may be clinically accessible, persuading the development of investigation in this field.
摘要:
大脑中β-淀粉样蛋白斑块的积累导致阿尔茨海默病(AD),神经退行性疾病.AD的永久性治疗尚不可用。目前的药物选择只能减缓其进步。然而,纳米技术已被证明在医学应用中是有利的。它对AD治疗有很大的潜力,特别是在诊断病情和提供替代治疗过程。在这次审查中,我们概述了纳米药物在治疗AD方面的进展和益处。用于诊断和监测AD和其他中枢神经系统(CNS)疾病的治疗干预的前瞻性纳米药物可能是临床上可获得的,说服这一领域调查的发展。
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