关键词: Bisphosphonate Bone mineral density Chronic kidney disease-mineral bone disorder Chronic renal insufficiency DXA Denosumab Dialysis FRAX Kidney transplant Mineral metabolism Osteoporosis Parathyroid hormone Renal osteodystrophy Vitamin D

来  源:   DOI:10.1159/000526492   PDF(Pubmed)

Abstract:
UNASSIGNED: The aim of this study was to reach a consensus on an updated version of the recommendations for the diagnosis and Treat-to-Target management of osteoporosis that is effective and safe for individuals with chronic kidney disease (CKD) G4-G5D/kidney transplant.
UNASSIGNED: Delphi process was implemented (3 rounds) to establish a consensus on 10 clinical domains: (1) study targets, (2) risk factors, (3) diagnosis, (4) case stratification, (5) treatment targets, (6) investigations, (7) medical management, (8) monitoring, (9) management of special groups, (10) fracture liaison service. After each round, statements were retired, modified, or added in view of the experts\' suggestions, and the percent agreement was calculated. Statements receiving rates of 7-9 by more than 75% of experts\' votes were considered as achieving consensus.
UNASSIGNED: The surveys were sent to an expert panel (n = 26), of whom 23 participated in the three rounds (2 were international experts and 21 were national). Most of the participants were rheumatologists (87%), followed by nephrologists (8.7%), and geriatric physicians (4.3%). Eighteen recommendations, categorized into 10 domains, were obtained. Agreement with the recommendations (rank 7-9) ranged from 80 to 100%. Consensus was reached on the wording of all 10 clinical domains identified by the scientific committee. An algorithm for the management of osteoporosis in CKD has been suggested.
UNASSIGNED: A panel of international and national experts established a consensus regarding the management of osteoporosis in CKD patients. The developed recommendations provide a comprehensive approach to assessing and managing osteoporosis for all healthcare professionals involved in its management.
摘要:
UNASSIGNED:这项研究的目的是就骨质疏松症的诊断和治疗目标管理建议的更新版本达成共识,该建议对患有慢性肾脏疾病(CKD)G4-G5D/肾移植的个体是有效和安全的。
UNASSIGNED:实施了Delphi过程(3轮),以建立10个临床领域的共识:(1)研究目标,(2)风险因素,(3)诊断,(4)病例分层,(5)治疗目标,(六)调查,(7)医疗管理,(8)监测,(9)特殊群体的管理,(10)骨折联络服务。每一轮之后,声明已经退休,已修改,或根据专家的建议添加,并计算了百分比协议。超过75%的专家投票率为7-9的声明被认为已达成共识。
未经评估:调查已发送给专家小组(n=26),其中23人参加了三轮(2人是国际专家,21人是国家专家)。大多数参与者是风湿病学家(87%),其次是肾病学家(8.7%),和老年医学医师(百分之四点三)。18条建议,分为10个领域,已获得。与建议(等级7-9)的一致性范围为80%至100%。就科学委员会确定的所有10个临床领域的措辞达成了共识。已提出了一种治疗CKD骨质疏松症的算法。
UNASSIGNED:国际和国家专家小组就CKD患者骨质疏松症的治疗达成共识。所制定的建议为参与其管理的所有医疗保健专业人员提供了评估和管理骨质疏松症的综合方法。
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