Abstract：
Penicillium oxalicum has been reported as a multienzyme-producing fungus and is widely used in industry due to great potential for cellulase release. Until now, there are only 10 available genome assemblies of P. oxalicum species deposited in the GenBank database. In this study, the genome of the I1R1 strain isolated from the root of Ixora chinensis was completely sequenced by Pacbio Sequel sequencing technology, assembled into 8 chromosomes with the genome size of 30.8 Mb, as well as a mitogenome of 26 kb. The structural and functional analyses of the I1R1 genome revealed gene model annotations encoding an enzyme set involved in significant metabolic processes, along with cytochrome P450s and secondary metabolite biosynthesis. The comparative analysis of the P. oxalicum species based on orthology and gene family duplications indicated their large and closed pan-genome of 9,500 orthologous groups. This is valuable data for future phylogenetic and population genomics studies.
摘要：
据报道，草酸青霉是一种产生多酶的真菌，由于释放纤维素酶的潜力很大，因此在工业中得到了广泛的应用。直到现在,在GenBank数据库中，只有10个可用的草酸疟原虫的基因组集合。在这项研究中,通过PacbioSequel测序技术对从Ixora根分离的I1R1菌株的基因组进行了完整测序，组装成8条染色体，基因组大小为30.8Mb，以及26kb的有丝分裂基因组。I1R1基因组的结构和功能分析揭示了编码参与重要代谢过程的酶集的基因模型注释，以及细胞色素P450和次级代谢产物的生物合成。基于正交学和基因家族重复的草酸疟原虫物种的比较分析表明，它们的9,500个直系同源群的大型和封闭的全基因组。这是未来系统发育和群体基因组学研究的宝贵数据。
