Abstract:
Steven-Johnson syndrome (SJS) is a serious disorder affecting the skin and mucous membrane, causing multiple flaccid bullae and purpuric rashes with sheet-like epithelial detachment including the ocular surface. The long-term outcomes following SJS are dismal and manifest as corneal vascularization, lid-wiper keratopathy, and severe dry eyes. The disease course can be modified if amniotic membrane graft is performed at the first week of disease, and the above-said complications can be avoided. This procedure thus not only decreases the morbidity but also improves the quality of life.
This video discusses the long-term sequelae of SJS which can be modified with timely intervention during the acute stage and thus significantly decreases morbidity.
The video demonstrates the simple technique of amniotic membrane transplantation in the acute stage in SJS and its impact in long run.
There should be a low threshold for doing early amniotic membrane transplantation in patients with SJS with ocular surface involvement. Early intervention can change the disease course and decrease disease morbidity significantly.
https://youtu.be/qgIiVcW56Oo.
摘要:
Steven-Johnson综合征(SJS)是一种严重影响皮肤和粘膜的疾病,引起多个松弛性大疱和紫癜性皮疹,包括眼表在内的片状上皮脱离。SJS后的长期结果令人沮丧,并表现为角膜血管化,眼睑刮水器角膜病变,严重的眼睛干涩。如果在疾病的第一周进行羊膜移植,则可以修改病程。上述并发症是可以避免的。因此,这种方法不仅降低了发病率,而且提高了生活质量。
本视频讨论了SJS的长期后遗症,可以在急性期通过及时干预进行修改,从而显着降低发病率。
视频展示了SJS急性期羊膜移植的简单技术及其长期影响。
对于有眼表受累的SJS患者,早期羊膜移植应具有较低的阈值。早期干预可显著改变病程,降低发病率。
https://youtu。是/qgIiVcW56Oo。