关键词: Poisoning case report dapsone methemoglobinemia

Mesh : Female Humans Adolescent Methemoglobinemia / chemically induced diagnosis drug therapy Dapsone Charcoal / therapeutic use Ascorbic Acid Tachypnea

来  源:   DOI:10.11604/pamj.2022.43.20.34069   PDF(Pubmed)

Abstract:
Methemoglobinemia is a common complication of dapsone poisoning. Its´ treatment usually relies on methylene blue infusion. The aim of this study was to report a case of an acute dapsone poisoning with methemoglobinemia treated only with ascorbic acid and activated charcoal. A 16-year-old female voluntary ingested 3 grams of dapsone in an attempt of suicide and presented with desaturation and tachypnea. Lab findings were compatible with methemoglobinemia. After two days of treatment with ascorbic acid and activated charcoal, we observed the disappearance of desaturation and tachypnea. Methemoglobinemia can be treated with ascorbic acid and activated charcoal in limited resource settings.
摘要:
高铁血红蛋白血症是氨苯砜中毒的常见并发症。其治疗通常依赖于亚甲蓝输注。这项研究的目的是报告一例急性氨苯砜中毒,仅使用抗坏血酸和活性炭治疗高铁血红蛋白血症。一名16岁的女性自愿摄入3克氨苯砜,企图自杀,并表现为去饱和和呼吸急促。实验室检查结果与高铁血红蛋白血症相符。用抗坏血酸和活性炭处理两天后,我们观察到去饱和和呼吸急促的消失。在有限的资源环境中,可以用抗坏血酸和活性炭治疗高铁血红蛋白血症。
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