Abstract:
Prostate cancer morbidity and mortality are increasing globally and in China, and the rate of metastasis is also rising, limiting the therapeutic effect and clinical prognosis of prostate cancer. CD151 is considered to be the first promoter of tumor metastasis in the tetraspanin superfamily. Previous research has linked CD151 to the progression of a number of malignancies, including prostate cancer. However, a recent study found that CD151 can inhibit the progression of prostate cancer. As a result, this paper examines existing research on CD151 and prostate cancer progression in order to clarify the relationship and provide a possible reference for future studies.
摘要:
前列腺癌的发病率和死亡率在全球和中国都在增加,转移率也在上升,限制前列腺癌的治疗效果和临床预后。CD151被认为是四跨膜蛋白超家族中肿瘤转移的第一个启动子。先前的研究已经将CD151与许多恶性肿瘤的进展联系起来,包括前列腺癌.然而,最近的一项研究发现,CD151可以抑制前列腺癌的进展。因此,本文对CD151与前列腺癌进展的相关研究进行了综述,以期阐明两者的关系,为今后的研究提供可能的参考。