关键词: Children Down syndrome Floppy muscle Hypotonia Muscle tone Quantitative evaluation

Mesh : Child Humans Muscle Hypotonia / diagnosis etiology Databases, Genetic Knowledge

来  源:   DOI:10.1016/j.pediatrneurol.2022.11.001

Abstract:
Hypotonia is considered a determinant factor in multiple developmental disorders and is associated with various characteristics and morbidities. It is necessary to perform a systematic review to know which characteristics are described as associated with hypotonia in children and which methods are used for its diagnosis.
Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were used to develop the systematic review protocol. A search of databases (Pubmed, Cochrane, Web of Knowledge, among others) was performed in May 2021 to identify relevant studies. Those describing characteristics or tests of hypotonia assessment were included, excluding those that exclusively addressed peripheral hypotonia. Two reviewers evaluated the articles and collected the data in a table, noting the authors, date of publication, type of study, and characteristics or tests described in relation to hypotonia. The quality of the studies was also assessed, and data were extracted.
A total of 8778 studies were identified and analyzed, of which 45 met the inclusion criteria. Fifty-three characteristics associated with hypotonia and tests used for its evaluation were located, with pull to sit and vertical suspension being the most frequently referenced.
The characteristics associated with hypotonia, more highly debated by authors are muscle strength, hypermobility, or the maintenance of antigravity postures. The most used test in the diagnosis of hypotonia is observation, followed by the pull-to-sit test, and adoption of frog posture. A unanimous understanding of the term hypotonia would favor further research.
摘要:
背景:低张力被认为是多种发育障碍的决定因素,并与各种特征和发病率相关。有必要进行系统回顾,以了解哪些特征被描述为与儿童张力减退有关,以及哪些方法用于其诊断。
方法:使用系统评价和Meta分析(PRISMA)指南的首选报告项目来制定系统评价方案。数据库搜索(Pubmed,科克伦,WebofKnowledge,除其他外)于2021年5月进行,以确定相关研究。包括描述低张力评估的特征或测试,不包括那些专门解决外周张力过低的患者。两名审稿人对文章进行了评估,并将数据收集在一个表中,注意到作者,发布日期,研究类型,以及与张力减退有关的特征或测试。还评估了研究的质量,并提取数据。
结果:共确定和分析了8778项研究,其中45人符合纳入标准。定位了与低张力相关的53个特征和用于其评估的测试,以拉坐和垂直悬挂是最经常提到的。
结论:与低张力相关的特征,作者更高度争论的是肌肉力量,高流动性,或保持反重力姿势。在低张力症的诊断中最常用的测试是观察,接下来是静坐测试,并采用青蛙姿势。对张力减退一词的一致理解将有利于进一步的研究。
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