关键词: hepatectomy hepatic cysts intrahepatic biliary cystadenoma intraoperative frozen section malignant transformation recurrence

来  源:   DOI:10.3389/fonc.2022.1003885   PDF(Pubmed)

Abstract:
UNASSIGNED: Intrahepatic biliary cystadenoma (IBC) is a rare benign cystic tumor of the liver. So far, it has not been comprehensively understood, which causes incorrect diagnosis, treatment confusion, and even inappropriate treatment. Here, we reviewed clinical data of IBC patients in our center, shared our experiences and lessons learned, and improved the level of diagnosis and treatment.
UNASSIGNED: The clinical data of 10 patients with pathologically diagnosed IBC, admitted to the Department of Hepatobiliary Surgery of the Affiliated Hospital of Guangdong Medical University from January, 2007, to January, 2022 were retrospectively analyzed.
UNASSIGNED: 10 patients underwent surgery and were discharged successfully. Cyst morphology: multiple cysts: 6 cases (6/10), monocular cyst: four cases(4/10). Six patients (6/10) were diagnosed as IBC preoperatively and received hepatectomy. Four patients with monocular cyst IBC underwent intraoperative frozen section examination, except one case showed IBC; the rest were misdiagnosed as simple liver cyst. In three misdiagnosed patients, one underwent open left hepatectomy seven days after the initial operation. The other patient refused to undergo reoperation and required follow-up observation. The last patient could not tolerate hepatectomy due to insufficient residual liver volume and chose follow-up observation.
UNASSIGNED: For IBC, especially monocular IBC, it is easy to be misdiagnosed as simple hepatic cyst, which brings great confusion to clinical treatment. We propose strengthening communication with pathologists to deepen understanding of IBC. Attention should be paid to the cyst wall\'s shape and the cyst fluid\'s properties during the operation to avoid the missed diagnosis, misdiagnosis, or even improper operation. For suspicious cases, directly choose hepatectomy to avoid reoperation after thoroughly evaluating the patient\'s condition.
摘要:
未经证实:肝内胆管囊腺瘤(IBC)是一种罕见的肝脏良性囊性肿瘤。到目前为止,它还没有得到全面的理解,导致错误的诊断,治疗混乱,甚至不适当的治疗。这里,我们回顾了我们中心IBC患者的临床数据,分享我们的经验和教训,提高了诊疗水平。
UNASSIGNED:10例经病理诊断为IBC的患者的临床资料,1月入住广东医科大学附属医院肝胆外科,2007年1月,2022年进行回顾性分析。
UNASSIGNED:10例患者接受了手术并成功出院。囊肿形态:多发囊肿6例(6/10),单眼囊肿4例(4/10)。6例患者(6/10)术前诊断为IBC并接受肝切除术。4例单眼囊肿IBC患者行术中冰冻切片检查,除1例显示IBC外,其余均误诊为单纯性肝囊肿。在三个误诊的病人中,其中一例在初次手术后7天接受了左肝开放切除术.另一名患者拒绝接受再次手术,需要随访观察。末例患者因残肝体积不足,不能耐受肝切除,选择随访观察。
未经评估:对于IBC,尤其是单眼IBC,容易误诊为单纯性肝囊肿,给临床治疗带来很大的困惑。我们建议加强与病理学家的沟通,以加深对IBC的理解。术中应注意囊壁的形态和囊液的性质,避免漏诊。误诊,甚至操作不当。对于可疑案件,在彻底评估患者病情后,直接选择肝切除术以避免再次手术。
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