Abstract：
Older people with dementia (PWD) in nursing homes (NHs) tend to have decreased cognitive function, which may cause behavioral and psychological symptoms of dementia (BPSDs) and hinder activities of daily living (ADLs). Therefore, taking measures against the cognitive decline of PWD in NH and, in turn, the decline of BPSDs and ADLs is crucial. The purpose of this study was to test whether a multimodal non-pharmacological intervention (MNPI) is effective in maintaining and improving global cognitive function, BPSDs, and ADLs in PWD in NHs.
An intervention study using a single-case AB design was conducted in three subjects in NHs. During the non-intervention phase, participants underwent follow-up assessments, and during the intervention phase, they participated in an MNPI. The ABC Dementia Scale (which concurrently assesses ADLs [\"A\"], BPSDs [\"B\"], and cognitive function [\"C\"]) was used for the assessment.
One of the three patients showed improvement in dementia severity, global cognitive function, ADLs, and BPSDs. However, the other two participants showed no improvement following the MNPI, although the possibility of a maintenance effect remained.
Although there is room for improvement of the MNPI, it may be effective in maintaining and improving cognitive function, ADLs, and BPSD, in PWD in NHs.
The University Hospital Medical Information Network Clinical Trials Registry ( http://www.umin.ac.jp/ , No. UMIN000045858, registration date: November 1, 2021).
An intervention study using a single-case AB design was conducted in three subjects in NHs. During the non-intervention phase, participants underwent follow-up assessments, and during the intervention phase, they participated in an MNPI. The ABC Dementia Scale (which concurrently assesses ADLs [\"A\"], BPSDs [\"B\"], and cognitive function [\"C\"]) was used for the assessment.
One of the three patients showed improvement in dementia severity, global cognitive function, ADLs, and BPSDs. However, the other two participants showed no improvement following the MNPI, although the possibility of a maintenance effect remained.
Although there is room for improvement of the MNPI, it may be effective in maintaining and improving cognitive function, ADLs, and BPSD, in PWD in NHs.
The University Hospital Medical Information Network Clinical Trials Registry ( http://www.umin.ac.jp/ , No. UMIN000045858, registration date: November 1, 2021).
摘要：
养老院（NHs）中的老年痴呆症（PWD）患者往往认知功能下降，这可能会导致痴呆（BPSD）的行为和心理症状，并阻碍日常生活活动（ADLs）。因此,采取措施预防NH和PWD的认知能力下降，反过来,BPSD和ADLs的下降至关重要。这项研究的目的是测试多模式非药物干预（MNPI）是否有效维持和改善全球认知功能，BPSD,和NHs中PWD中的ADL。
在NHs的三名受试者中进行了使用单病例AB设计的干预研究。在非干预阶段，参与者接受了后续评估，在干预阶段，他们参加了MNPI。ABC痴呆症量表(同时评估ADL[\“A\”]，BPSD[\"B\"],和认知功能[\“C\”])用于评估。
三位患者中的一位表现出痴呆严重程度的改善，全局认知功能，ADLs,和BPSD。然而,另外两名参与者在MNPI之后没有任何改善，虽然维持效果的可能性仍然存在。
虽然MNPI还有改进的空间，它可以有效地维持和改善认知功能，ADLs,和BPSD，在NHs的PWD中。
大学医院医疗信息网络临床试验注册(http://www.乌明。AC.jp/,不。UMIN000045858，注册日期：2021年11月1日）。
在NHs的三名受试者中进行了使用单病例AB设计的干预研究。在非干预阶段，参与者接受了后续评估，在干预阶段，他们参加了MNPI。ABC痴呆症量表(同时评估ADL[\“A\”]，BPSD[\"B\"],和认知功能[\“C\”])用于评估。
三位患者中的一位表现出痴呆严重程度的改善，全局认知功能，ADLs,和BPSD。然而,另外两名参与者在MNPI之后没有任何改善，虽然维持效果的可能性仍然存在。
虽然MNPI还有改进的空间，它可以有效地维持和改善认知功能，ADLs,和BPSD，在NHs的PWD中。
大学医院医疗信息网络临床试验注册(http://www.乌明。AC.jp/,不。UMIN000045858，注册日期：2021年11月1日）。
