Abstract:
Sweat is an important biofluid presents in the body since it regulates the internal body temperature, and it is relatively easy to access on the skin unlike other biofluids and contains several biomarkers that are also present in the blood. Although sweat sensing devices have recently displayed tremendous progress, most of the emerging devices primarily focus on the sensor development, integration with electronics, wearability, and data from in vitro studies and short-term on-body trials during exercise. To further the advances in sweat sensing technology, this review aims to present a comprehensive report on the approaches to access and manage sweat from the skin toward improved sweat collection and sensing. It is begun by delineating the sweat secretion mechanism through the skin, and the historical perspective of sweat, followed by a detailed discussion on the mechanisms governing sweat generation and management on the skin. It is concluded by presenting the advanced applications of sweat sensing, supported by a discussion of robust, extended-operation epidermal wearable devices aiming to strengthen personalized healthcare monitoring systems.
摘要:
汗水是一种重要的生物流体存在于体内,因为它调节内部体温,与其他生物流体不同,它相对容易在皮肤上接触,并且含有几种也存在于血液中的生物标志物。虽然汗液传感设备最近显示出巨大的进步,大多数新兴设备主要专注于传感器的开发,与电子产品集成,可穿戴性,以及来自体外研究和运动期间短期身体试验的数据。为了进一步推进汗液传感技术的进步,这篇综述旨在提供一份全面的报告,介绍从皮肤获取和管理汗液的方法,以改善汗液的收集和感知。它是通过描绘通过皮肤的汗液分泌机制开始的,和汗水的历史视角,随后详细讨论了控制皮肤汗液产生和管理的机制。最后介绍了汗液传感的先进应用,在关于健壮的讨论的支持下,扩展操作表皮可穿戴设备,旨在加强个性化医疗监测系统。