Abstract：
The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application of olive oil versus other products for PU prevention. We assessed the risk of bias using the RoB 2 tool, and the certainty of the evidence with GRADE. Four RCTs met the eligibility criteria. All studies were judged at a low risk of bias overall. The meta-analysis showed that the clinical efficacy of olive oil for prevention occurs by reducing the incidence of PUs (RR = 0.56, 95% CI = 0.30 to 0.79, I2 = 0%); with no differences in adverse effects, it may be associated with a shorter development time of PUs and shorter hospital stays. The certainty of the evidence assessed by the GRADE approach was moderate and low. The topical application of olive oil is effective and safe in reducing the incidence of PUs compared to other treatments. These findings could provide new insights into olive oil as a preventive and alternative treatment for PUs as it is accessible and inexpensive compared to other products.
摘要：
目的是确定和总结有关局部使用橄榄油预防压疮（PU）的有效性和安全性的现有证据。我们只纳入了随机对照试验（RCT），涉及有患PU风险的患者，测试橄榄油与其他产品的局部应用以预防PU。我们使用RoB2工具评估了偏倚的风险，以及等级证据的确定性。四个RCT符合资格标准。所有研究的总体偏倚风险较低。荟萃分析显示，橄榄油预防的临床疗效是通过降低PU的发生率（RR=0.56，95％CI=0.30至0.79，I2=0％）；不良反应无差异，它可能与较短的PU发展时间和较短的住院时间有关.通过GRADE方法评估的证据的确定性是中等和较低的。与其他治疗方法相比，局部使用橄榄油可有效且安全地降低PU的发生率。这些发现可以为橄榄油作为PU的预防和替代疗法提供新的见解，因为与其他产品相比，它是可获得且便宜的。
