PDF(Pubmed)
Abstract：
The Sertoli cell tumor of the ovary is a rare ovarian tumor with non-specific symptoms. According to the literature, endocrine manifestations occur in two-thirds of patients, but testosterone production is extremely rare. Typically, it is a unilateral benign tumor of the ovary that most commonly presents in adolescents and young women of childbearing potential. We report a 29-year-old patient, previously diagnosed to have polycystic ovarian syndrome, who presented with complaints of amenorrhea for the past three years. A transvaginal ultrasound scan revealed polycystic structure ovaries and a solid cystic formation of 32 × 31 mm size with strong blood flow in the left ovary. The laboratory tests reported an elevated testosterone level. During laparoscopic surgery, a solid, yellowish tumor was removed and the left ovary was resected. Histological examination revealed a left ovary Sertoli cell tumor with an immature prepubertal-like Sertoli cell component. Following surgery, the serum testosterone levels returned to normal and the menstrual cycle became regular. Due to the substantially low incidence of ovarian Sertoli cell tumors, information on their clinical behavior, morphologic spectrum, optimal management, and prognosis is limited. They are characterized by a wide variety of clinical manifestations, treated surgically, and, if diagnosed at an early stage, have good prognosis. We emphasize the extraordinarily rare clinical presentation of this case report.
摘要：
卵巢支持细胞瘤是一种罕见的具有非特异性症状的卵巢肿瘤。根据文献,三分之二的患者出现内分泌表现，但是睾丸激素的产生极为罕见。通常,它是一种单侧卵巢良性肿瘤，最常见于有生育潜力的青少年和年轻女性。我们报告了一个29岁的病人,以前被诊断患有多囊卵巢综合征，在过去的三年里，他一直抱怨闭经。经阴道超声扫描显示多囊结构卵巢和32×31毫米大小的实性囊性形成，左侧卵巢血流旺盛。实验室测试报告睾酮水平升高。在腹腔镜手术期间，一个固体，切除黄色肿瘤，切除左卵巢。组织学检查显示左卵巢支持细胞肿瘤，具有未成熟的青春期前支持细胞成分。手术后,血清睾酮水平恢复正常,月经周期正常.由于卵巢支持细胞肿瘤的发病率相当低，关于他们临床行为的信息，形态光谱,优化管理，预后有限。他们的特点是各种各样的临床表现，手术治疗，and,如果在早期诊断，预后良好。我们强调这种病例报告的非常罕见的临床表现。
