跨隔室边界操作的动态质量控制机器介导哺乳动物核膜蛋白的降解。
关键词: CP: Molecular biology CRISPR screen ERAD RNF5 TMEM33 nuclear envelopathies proteasome protein quality control protein turnover proteostasis ubiquitin ligase
Mesh : Animals Humans Ubiquitin-Protein Ligases / metabolism Membrane Proteins / metabolism Endoplasmic Reticulum / metabolism Ubiquitin-Conjugating Enzymes / metabolism Ubiquitin / metabolism Mammals / metabolism
来 源:
DOI:10.1016/j.celrep.2022.111675
PDF(Pubmed)