Abstract：
COVID-19 most related glomerular disease to date seems to be collapsing glomerulopathy, mostly in young Afroamerican patients with APOL1 gene risk alleles. However, in our population, predominant in elderly Caucasian patients, most biopsied pathology since the beginning of the pandemic has been IgA nephritis or Schönlein-Henoch purpura. Since the description of the first case of this entity after SARS-CoV-2 infection by our research group, three more cases have arisen, which are described in the following article. In contrast to the rest of IgA vasculitis cases reported, our patients presented more renal function deterioration and all of them required immunosupresive therapy. Moreover, some showed incomplete recovery of renal function. This case series strengthens the hypothesis that SARS-CoV-2 infection may be another trigger of this pathology.
摘要：
迄今为止，COVID-19最相关的肾小球疾病似乎是塌陷性肾小球病，多数在年轻的非洲裔患者中具有APOL1基因风险等位基因。然而,在我们的人口中，在老年高加索患者中占主导地位，自大流行开始以来,大多数活检病理为IgA肾炎或过敏性紫癜.自从我们的研究小组描述了SARS-CoV-2感染后的第一例该实体以来，又出现了三个案例，这在下面的文章中描述。与报告的其他IgA血管炎病例相反，我们的患者出现更多的肾功能恶化,所有患者都需要免疫抑制治疗.此外，有的显示肾功能不完全恢复。此病例系列加强了以下假设：SARS-CoV-2感染可能是这种病理的另一个触发因素。
