UNASSIGNED: Demographic characteristics, patient clinical information, and laboratory data of 81,131 patients with respiratory tract infections (RTIs) in the Affiliated Suzhou Hospital of Nanjing Medical University from 2014 to 2020 were retrospectively collected from all patient records. The serum particle agglutination (PA) test was used to determine M. Pneumoniae infection by detecting specific antibodies. The white blood cell count, the proportion of neutrophils and lymphocytes, C-reactive protein (CRP) and lactate dehydrogenase (LDH) levels between children and adults with SMPP were compared by Student\'s t-test; other clinical features were analyzed by χ2 test or Fisher\'s exact test.
UNASSIGNED: A total of 81,131 patients with RTIs were included, and 21,582 (26.60%) M. Pneumoniae immunoglobulin M (IgM)-positive patients were detected. From 2014 to 2020, the annual proportions of M. Pneumoniae RTIs were 23.60%, 28.18%, 38.08%, 27.05%, 23.44%, 25.26%, and 18.33%, respectively. In terms of seasonal distribution, April-June and September-November were the peak seasons of M. Pneumoniae infection each year. Children and women have a high proportion of M. Pneumoniae infection. The peak age of M. Pneumoniae infection was between 4 and 14 years old. There were 301 cases of SMPP, including 281 children and 20 adults (8 cases of pregnant women). Children and pregnant women accounted for a high proportion of SMPP. Children with SMPP had more extrapulmonary symptoms, multilobar infiltrates, and increased CRP and LDH levels compared with adults.
UNASSIGNED: M. Pneumoniae infection has seasonal, sex, and age distribution trends. Children and pregnant women accounted for a high proportion of SMPP. Extrapulmonary symptoms, multilobar infiltrates, and increased CRP and LDH levels may be helpful to identify SMPP in children than in adults.
未经评估:人口统计学特征,患者临床信息,回顾性收集2014年至2020年南京医科大学附属苏州医院81,131例呼吸道感染(RTIs)患者的实验室资料。血清颗粒凝集(PA)试验用于通过检测特异性抗体来确定肺炎支原体感染。白细胞计数,中性粒细胞和淋巴细胞的比例,儿童和成人SMPP患者C反应蛋白(CRP)和乳酸脱氢酶(LDH)水平比较采用t检验,其他临床特征采用χ2检验或Fisher精确检验。
未经授权:共纳入81,131例RTIs患者,检出肺炎支原体免疫球蛋白M(IgM)阳性患者21582例(26.60%)。从2014年到2020年,肺炎支原体RTIs的年度比例为23.60%,28.18%,38.08%,27.05%,23.44%,25.26%,和18.33%,分别。从季节分布来看,每年的4-6月和9-11月是肺炎支原体感染的高峰季节。儿童和妇女肺炎支原体感染的比例很高。肺炎支原体感染的高峰年龄在4至14岁之间。有301例SMPP,其中儿童281例,成人20例(孕妇8例)。儿童和孕妇在SMPP中所占比例较高。SMPP患儿有更多的肺外症状,多叶浸润物,与成人相比,CRP和LDH水平升高。
未经批准:M肺炎感染具有季节性,性别,和年龄分布趋势。儿童和孕妇在SMPP中所占比例较高。肺外症状,多叶浸润物,与成人相比,CRP和LDH水平升高可能有助于识别儿童的SMPP。