PDF(Pubmed)
Abstract：
UNASSIGNED: Chemotherapy and radiation therapy given to treat internal malignancies may cause cutaneous, hair, nail, and oral mucosal changes. The present study is an effort to know the pattern of cutaneous drug reactions with chemo and radiotherapy.
UNASSIGNED: Patients of internal malignancies with skin lesions attending the dermatology and oncology OPD/ward were recruited after taking their written consent in vernacular language. A detailed history of skin lesions, malignancies, and treatment was taken. Clinical examination was carried out. Relevant investigations and biopsy were carried out as and when required. Being a descriptive study, age group and gender-wise frequency and percentage were calculated for the treatment of malignancies and dermatosis.
UNASSIGNED: The study included 150 patients with 28 different types of internal malignancies, of which 127 (84.66%) patients were treated, 45 (35.43%) treated exclusively with chemotherapy, 16 (12.59%) with exclusive radiation therapy, and 66 (51.96%) with combined chemo and radiation therapy. Total 111 (87.41%) patients received chemotherapy and 82 (64.56%) patients received radiation therapy. Most common internal malignancy was breast carcinoma in 43 (28.67%) cases. Most common chemotherapeutic agent given was paclitaxel to 33 (29.73%) patients. Most common dermatosis associated with exclusive chemotherapy was hand-foot syndrome in 7 (15.55%) cases and with exclusive radiation therapy was radiation dermatitis in 8 (50%) cases.
UNASSIGNED: The study was useful in understanding various chemo and radiation therapy-associated dermatosis so that early interventions can be done to prevent further treatment-related adverse effects.
UNASSIGNED: Small sample size and inability of pinpointing a single drug as the side effect.
UNASSIGNED: Patients of internal malignancies with skin lesions attending the dermatology and oncology OPD/ward were recruited after taking their written consent in vernacular language. A detailed history of skin lesions, malignancies, and treatment was taken. Clinical examination was carried out. Relevant investigations and biopsy were carried out as and when required. Being a descriptive study, age group and gender-wise frequency and percentage were calculated for the treatment of malignancies and dermatosis.
UNASSIGNED: The study included 150 patients with 28 different types of internal malignancies, of which 127 (84.66%) patients were treated, 45 (35.43%) treated exclusively with chemotherapy, 16 (12.59%) with exclusive radiation therapy, and 66 (51.96%) with combined chemo and radiation therapy. Total 111 (87.41%) patients received chemotherapy and 82 (64.56%) patients received radiation therapy. Most common internal malignancy was breast carcinoma in 43 (28.67%) cases. Most common chemotherapeutic agent given was paclitaxel to 33 (29.73%) patients. Most common dermatosis associated with exclusive chemotherapy was hand-foot syndrome in 7 (15.55%) cases and with exclusive radiation therapy was radiation dermatitis in 8 (50%) cases.
UNASSIGNED: The study was useful in understanding various chemo and radiation therapy-associated dermatosis so that early interventions can be done to prevent further treatment-related adverse effects.
UNASSIGNED: Small sample size and inability of pinpointing a single drug as the side effect.
摘要：
未经批准：用于治疗内部恶性肿瘤的化疗和放疗可能会导致皮肤，头发,钉,口腔粘膜改变.本研究旨在了解化学和放射疗法引起的皮肤药物反应模式。
UNASSIGNED：在皮肤科和肿瘤科OPD/病房接受书面同意后，招募了患有内部恶性肿瘤的皮肤病变的患者。详细的皮肤损伤史，恶性肿瘤,并进行了治疗。进行临床检查。必要时进行相关调查和活检。作为一项描述性研究，根据年龄分组和性别计算恶性肿瘤和皮肤病治疗的频率和百分比.
UNASSIGNED：该研究包括150名患者，他们患有28种不同类型的内部恶性肿瘤，其中127例(84.66%)患者接受治疗，45例（35.43%）仅接受化疗，16人（12.59%）接受独家放射治疗，66例(51.96%)接受化疗和放疗联合治疗。111例（87.41%）患者接受化疗，82例（64.56%）患者接受放疗。最常见的内部恶性肿瘤是43例（28.67％）乳腺癌。最常见的化疗药物是紫杉醇治疗33例（29.73%）。与唯一化疗相关的最常见皮肤病是7例（15.55％）手足综合征，与唯一放疗相关的最常见皮肤病是8例（50％）放射性皮炎。
UNASSIGNED：该研究有助于了解各种化学和放射疗法相关的皮肤病，从而可以进行早期干预以防止进一步的治疗相关不良反应。
UNASSIGNED：样本量小，无法确定单一药物的副作用。
UNASSIGNED：在皮肤科和肿瘤科OPD/病房接受书面同意后，招募了患有内部恶性肿瘤的皮肤病变的患者。详细的皮肤损伤史，恶性肿瘤,并进行了治疗。进行临床检查。必要时进行相关调查和活检。作为一项描述性研究，根据年龄分组和性别计算恶性肿瘤和皮肤病治疗的频率和百分比.
UNASSIGNED：该研究包括150名患者，他们患有28种不同类型的内部恶性肿瘤，其中127例(84.66%)患者接受治疗，45例（35.43%）仅接受化疗，16人（12.59%）接受独家放射治疗，66例(51.96%)接受化疗和放疗联合治疗。111例（87.41%）患者接受化疗，82例（64.56%）患者接受放疗。最常见的内部恶性肿瘤是43例（28.67％）乳腺癌。最常见的化疗药物是紫杉醇治疗33例（29.73%）。与唯一化疗相关的最常见皮肤病是7例（15.55％）手足综合征，与唯一放疗相关的最常见皮肤病是8例（50％）放射性皮炎。
UNASSIGNED：该研究有助于了解各种化学和放射疗法相关的皮肤病，从而可以进行早期干预以防止进一步的治疗相关不良反应。
UNASSIGNED：样本量小，无法确定单一药物的副作用。
