UNASSIGNED: Patients of internal malignancies with skin lesions attending the dermatology and oncology OPD/ward were recruited after taking their written consent in vernacular language. A detailed history of skin lesions, malignancies, and treatment was taken. Clinical examination was carried out. Relevant investigations and biopsy were carried out as and when required. Being a descriptive study, age group and gender-wise frequency and percentage were calculated for the treatment of malignancies and dermatosis.
UNASSIGNED: The study included 150 patients with 28 different types of internal malignancies, of which 127 (84.66%) patients were treated, 45 (35.43%) treated exclusively with chemotherapy, 16 (12.59%) with exclusive radiation therapy, and 66 (51.96%) with combined chemo and radiation therapy. Total 111 (87.41%) patients received chemotherapy and 82 (64.56%) patients received radiation therapy. Most common internal malignancy was breast carcinoma in 43 (28.67%) cases. Most common chemotherapeutic agent given was paclitaxel to 33 (29.73%) patients. Most common dermatosis associated with exclusive chemotherapy was hand-foot syndrome in 7 (15.55%) cases and with exclusive radiation therapy was radiation dermatitis in 8 (50%) cases.
UNASSIGNED: The study was useful in understanding various chemo and radiation therapy-associated dermatosis so that early interventions can be done to prevent further treatment-related adverse effects.
UNASSIGNED: Small sample size and inability of pinpointing a single drug as the side effect.
UNASSIGNED:在皮肤科和肿瘤科OPD/病房接受书面同意后,招募了患有内部恶性肿瘤的皮肤病变的患者。详细的皮肤损伤史,恶性肿瘤,并进行了治疗。进行临床检查。必要时进行相关调查和活检。作为一项描述性研究,根据年龄分组和性别计算恶性肿瘤和皮肤病治疗的频率和百分比.
UNASSIGNED:该研究包括150名患者,他们患有28种不同类型的内部恶性肿瘤,其中127例(84.66%)患者接受治疗,45例(35.43%)仅接受化疗,16人(12.59%)接受独家放射治疗,66例(51.96%)接受化疗和放疗联合治疗。111例(87.41%)患者接受化疗,82例(64.56%)患者接受放疗。最常见的内部恶性肿瘤是43例(28.67%)乳腺癌。最常见的化疗药物是紫杉醇治疗33例(29.73%)。与唯一化疗相关的最常见皮肤病是7例(15.55%)手足综合征,与唯一放疗相关的最常见皮肤病是8例(50%)放射性皮炎。
UNASSIGNED:该研究有助于了解各种化学和放射疗法相关的皮肤病,从而可以进行早期干预以防止进一步的治疗相关不良反应。
UNASSIGNED:样本量小,无法确定单一药物的副作用。