METHODS: Fourteen consecutive outpatients with a secure diagnosis of IPF were recruited and the 10-item Eating Assessment Tool (Eat 10) used to assess patient perception of swallowing difficulty. Oropharyngeal swallowing was assessed in ten patients using Videofluoroscopy Swallow Studies (VFSS). The studies were rated using validated scales: Penetration-Aspiration Scale (PAS); standardised Modified Barium Swallow Impairment Profile (MBSImP).
RESULTS: EAT-10 scores indicated frank swallowing difficulty in 4/14 patients. Videofluoroscopy Studies showed that 3/10 patients had airway penetration, and one aspirated liquid without a cough response. Median MBSImp for oral impairment was 5, range [3-7] and pharyngeal impairment 4, range [1-14] indicating, overall mild alteration to swallowing physiology.
CONCLUSIONS: We conclude that people with IPF can show a range of swallowing dysfunction, including aspiration into an unprotected airway. To our knowledge, this is the first report on swallowing physiology and safety in IPF. We believe a proportion of this group may be at risk of aspiration. Further work is indicated to fully explore swallowing in this vulnerable group.
方法:招募了14例确诊为IPF的连续门诊患者,并使用10项饮食评估工具(Eat10)评估患者对吞咽困难的感知。使用透视吞咽研究(VFSS)评估了10例患者的口咽吞咽。使用经过验证的量表对研究进行了评估:穿透-抽吸量表(PAS);标准化的修改后的钡吞咽损伤谱(MBSIMP)。
结果:EAT-10评分显示4/14例患者有明显吞咽困难。视频透视研究显示,3/10的患者有气道穿透,和一个没有咳嗽反应的液体。口腔损害的MBSImp中位数为5,范围为[3-7],咽部损害为4,范围为[1-14],表明吞咽生理的总体轻度改变。
结论:我们得出结论,IPF患者可以表现出一系列吞咽功能障碍,包括吸入无保护的气道。据我们所知,这是关于IPF吞咽生理和安全性的第一份报告.我们认为,这一群体中的一部分人可能有抱负的风险。指出了进一步的工作,以充分探索这一弱势群体的吞咽行为。