关键词: HTLV-1 postural balance stabilometry tropical spastic paraparesis

Mesh : Humans Human T-lymphotropic virus 1 HTLV-I Infections Paraparesis, Tropical Spastic / diagnosis Diagnosis, Differential Healthy Volunteers

来  源:   DOI:10.3390/v14112334   PDF(Pubmed)

Abstract:
(1) Background: Tropical spastic paraparesis (TSP/HAM) associated with the T cell lymphotropic virus in type I humans (HTLV-1) is a slow, chronic, and progressive disease that causes balance changes. TSP/HAM diagnosis can be classified as probable, possible, and definite. We compared the static balance control of HTLV-1-infected patients with different TSP/HAM diagnosis. (2) Methods: Our sample consisted of 13 participants infected with HTLV-1 and 16 healthy participants. The center of pressure was recorded using a force platform with open and closed eyes. We divided the recordings into three intervals, period T1 (corresponds to the first 10 s); period T2 (from 10 to 45 s); period T3 (from 45 to 55 s). (3) Results: Eight participants infected with HTLV-1 were classified as probable TSP/HAM and five participants infected with HTLV-1 were classified as definite TSP/HAM. There was a significant increase in postural instability in patients with definite PET/MAH considering the structural and global variables of body sway compared to the control and the probable TSP/HAM. (4) Conclusions: We concluded that the severity of balance is directly related to the degree of signs and symptoms of TSP/HAM.
摘要:
(1)背景:与I型人类T细胞淋巴病毒(HTLV-1)相关的热带痉挛性轻瘫(TSP/HAM)是一种缓慢的,慢性,和导致平衡变化的进行性疾病。TSP/HAM诊断可以分类为可能,可能,和确定。我们比较了不同TSP/HAM诊断的HTLV-1感染患者的静态平衡控制。(2)方法:我们的样本包括13名感染HTLV-1的参与者和16名健康参与者。使用睁眼和闭眼的力平台记录压力中心。我们把录音分成三个间隔,周期T1(对应于前10秒);周期T2(从10到45秒);周期T3(从45到55秒)。(3)结果:八名感染HTLV-1的参与者被分类为可能的TSP/HAM,五名感染HTLV-1的参与者被分类为确定的TSP/HAM。考虑到身体摇摆的结构和全局变量,与对照组和可能的TSP/HAM相比,患有明确PET/MAH的患者的姿势不稳定性显着增加。(4)结论:我们得出结论,平衡的严重程度与TSP/HAM的体征和症状的程度直接相关。
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