Abstract:
Primary aldosteronism (PA) is the most frequent form of secondary endocrine hypertension, which is characterized by excessive aldosterone secretion and suppressed renin. The currently recommended diagnostic algorithm is very clear, and the plasma aldosterone-to-renin ratio (ARR) is considered the first-line screening test. However, this indicator is influenced by many factors, some of which may cause false-negative results, consequently leading to underdiagnosed PA. Here, we report the rare case of a 38-year-old man who presented with bilateral accessory renal arteries and aldosterone-producing adenoma but had a negative ARR test result.
摘要:
原发性醛固酮增多症(PA)是继发性内分泌高血压的最常见形式,其特征是醛固酮分泌过多和肾素抑制。目前推荐的诊断算法非常明确,血浆醛固酮与肾素比值(ARR)被认为是一线筛查试验.然而,这个指标受许多因素的影响,其中一些可能会导致假阴性结果,因此导致PA诊断不足。这里,我们报道了一例罕见病例,一名38岁男性患者出现双侧副肾动脉和醛固酮分泌腺瘤,但ARR检测结果为阴性.