关键词: Bariatric surgery Health outcomes Healthcare research Infertility Pregnancies Registry analysis

Mesh : Pregnancy Child Humans Female Child Health Obesity, Morbid / surgery Bariatric Surgery Fertility Austria Pregnancy Outcome Pregnancy Complications / epidemiology

来  源:   DOI:10.1007/s11695-022-06346-9

Abstract:
Bariatric surgery has a favorable effect on fertility in women. However, due to a lack of data regarding children\'s outcomes, the ideal time for conception following bariatric surgery is unknown. Current guidelines advise avoiding pregnancy during the initial weight loss phase (12-24 months after surgery) as there may be potential risks to offspring. Thus, we aimed to analyze health outcomes in children born to mothers who had undergone bariatric surgery. The surgery-to-delivery interval was studied.
A nationwide registry belonging to the Austrian health insurance funds and containing health-related data claims was searched. Data for all women who had bariatric surgery in Austria between 01/2010 and 12/2018 were analyzed. A total of 1057 women gave birth to 1369 children. The offspring\'s data were analyzed for medical health claims based on International Classification of Diseases (ICD) codes and number of days hospitalized. Three different surgery-to-delivery intervals were assessed: 12, 18, and 24 months.
Overall, 421 deliveries (31%) were observed in the first 2 years after surgery. Of these, 70 births (5%) occurred within 12 months after surgery. The median time from surgery to delivery was 34 months. Overall, there were no differences noted in frequency of hospitalization and diagnoses leading to hospitalization in the first year of life, regardless of the surgery-to-delivery interval.
Pregnancies in the first 24 months after bariatric surgery were common. Importantly, the surgery-to-delivery interval had no significant impact on the health outcome of the children.
摘要:
目的:减肥手术对女性的生育能力有良好的影响。然而,由于缺乏关于儿童结局的数据,减肥手术后的理想受孕时间未知.目前的指南建议在最初的减肥阶段(手术后12-24个月)避免怀孕,因为可能对后代有潜在的风险。因此,我们旨在分析接受减肥手术的母亲所生的儿童的健康状况.研究了手术至分娩间隔。
方法:搜索了属于奥地利健康保险基金并包含健康相关数据索赔的全国注册表。分析了2010年1月至2018年12月在奥地利接受减肥手术的所有女性的数据。共有1057名妇女生了1369个孩子。根据国际疾病分类(ICD)代码和住院天数,对后代的数据进行了医疗健康索赔分析。评估了三种不同的手术至分娩间隔:12、18和24个月。
结果:总体而言,手术后的前2年观察到421例(31%)分娩。其中,手术后12个月内有70例(5%)出生。从手术到分娩的中位时间为34个月。总的来说,在住院频率和诊断导致住院的第一年没有差异,无论手术至分娩间隔如何。
结论:减肥手术后的头24个月怀孕是常见的。重要的是,手术至分娩间隔时间对患儿的健康结局无显著影响.
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