关键词: COVID-19 NGS Real time RT-PCR SARS-CoV-2 TEM fecal

Mesh : Humans SARS-CoV-2 COVID-19 Sewage RNA, Viral Feces

来  源:   DOI:10.3389/fpubh.2022.1030249   PDF(Pubmed)

Abstract:
SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal-oral transmission may not be the main mode of transmission. Larger-scale initiatives are nevertheless required, particularly considering the emergence of new viral strains.
摘要:
SARS-CoV-2可以在粪便中脱落,并可以进入污水系统。为了实施有效的控制措施,确定新的传播渠道,必须确定粪便和污水中是否存在传染性病毒颗粒。在这项研究中,我们试图利用分子技术,细胞培养和动物模型,以了解SARS-CoV-2在COVID-19患者粪便中的传染性。我们的发现排除了感染性病毒颗粒的存在,这表明粪便-口腔传播可能不是主要的传播方式。然而,需要采取更大规模的举措,特别是考虑到新的病毒株的出现。
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