Abstract：
BACKGROUND: To investigate the possible effect of implantable collamer lens (ICL) V4c on ocular biometric measurements by a new biometer Pentacam-AXL and partial coherence interferometry (PCI)-based IOLMaster 500 and intraocular lens power calculation using fourth-generation formula.
METHODS: We retrospectively enrolled patients who underwent ICL (EVO-V4c, STAAR Surgical Co. Nidau, Switzerland) implantation surgery from September 2020 to November 2021. The Pentacam-AXL and IOLMaster 500 biometers were used to measure axial length (AL), anterior chamber depth (ACD), keratometry (K), white to white (WTW), and central corneal thickness (CCT) values before and at least 2 months after ICL V4c implantation. The IOL power was calculated using the Barrett Universal II formula.
RESULTS: The study included 45 eyes in 28 patients. There was a significant increase in ALs (average 0.03 ± 0.07 mm, p = 0.01) and a significant decrease of ACDs (average 0.19 ± 0.17 mm, p < 0.001) based on Pentacam-AXL. Similar changes in ALs and ACDs were also found in IOLMaster 500. In addition, the difference in WTWs in the two devices and that of CCTs in Pentacam-AXL were statistically significant. However, the preoperative and postoperative K1 and K2 were separately comparable using either device. The IOL power calculated by the Barrett Universal II formula did not change significantly either by the software built in Pentacam-AXL or by manually putting the parameters of the IOLMaster 500 into the formula manually (p = 0.058, p = 0.675, respectively).
CONCLUSIONS: Ocular parameters including ALs, ACDs, WTWs, and CCTs using a new Pentacam-AXL and standard PCI-based IOLMaster 500 changed significantly before and after the ICL V4c implantation, while IOL power prediction using the Barrett Universal II formula was little affected.
METHODS: We retrospectively enrolled patients who underwent ICL (EVO-V4c, STAAR Surgical Co. Nidau, Switzerland) implantation surgery from September 2020 to November 2021. The Pentacam-AXL and IOLMaster 500 biometers were used to measure axial length (AL), anterior chamber depth (ACD), keratometry (K), white to white (WTW), and central corneal thickness (CCT) values before and at least 2 months after ICL V4c implantation. The IOL power was calculated using the Barrett Universal II formula.
RESULTS: The study included 45 eyes in 28 patients. There was a significant increase in ALs (average 0.03 ± 0.07 mm, p = 0.01) and a significant decrease of ACDs (average 0.19 ± 0.17 mm, p < 0.001) based on Pentacam-AXL. Similar changes in ALs and ACDs were also found in IOLMaster 500. In addition, the difference in WTWs in the two devices and that of CCTs in Pentacam-AXL were statistically significant. However, the preoperative and postoperative K1 and K2 were separately comparable using either device. The IOL power calculated by the Barrett Universal II formula did not change significantly either by the software built in Pentacam-AXL or by manually putting the parameters of the IOLMaster 500 into the formula manually (p = 0.058, p = 0.675, respectively).
CONCLUSIONS: Ocular parameters including ALs, ACDs, WTWs, and CCTs using a new Pentacam-AXL and standard PCI-based IOLMaster 500 changed significantly before and after the ICL V4c implantation, while IOL power prediction using the Barrett Universal II formula was little affected.
摘要：
背景：通过一种新的基于Pentacam-AXL和部分相干干涉测量（PCI）的IOLMaster500和使用第四代公式的人工晶状体屈光力计算，研究植入式结缘晶状体（ICL）V4c对眼部生物特征测量的可能影响。
方法：我们回顾性招募了接受ICL的患者(EVO-V4c，STAAR外科公司Nidau,瑞士）从2020年9月至2021年11月进行植入手术。Pentacam-AXL和IOLMaster500生物计用于测量轴向长度（AL），前房深度（ACD），角膜曲率测量（K），白色至白色(WTW)，ICLV4c植入前和植入后至少2个月的中央角膜厚度（CCT）值。使用巴雷特通用II公式计算IOL功率。
结果：该研究包括28例患者的45只眼。AL显著增加(平均0.03±0.07毫米，p=0.01），ACDs显着下降（平均0.19±0.17mm，p<0.001)基于Pentacam-AXL。在IOLMaster500中也发现了AL和ACD的类似变化。此外,两种设备中WTWs和Pentacam-AXL中CCT的差异有统计学意义。然而,两种装置的术前和术后K1和K2分别具有可比性.通过Pentacam-AXL中内置的软件或通过手动将IOLMaster500的参数手动放入公式中（分别为p=0.058，p=0.675），由BarrettUniversalII公式计算的IOL功率没有显着变化。
结论：眼部参数，包括AL，ACD,WTW,使用新型Pentacam-AXL和基于标准PCI的IOLMaster500的CCT在ICLV4c植入前后发生了显着变化，而使用BarrettUniversalII公式预测IOL功率的影响很小。
方法：我们回顾性招募了接受ICL的患者(EVO-V4c，STAAR外科公司Nidau,瑞士）从2020年9月至2021年11月进行植入手术。Pentacam-AXL和IOLMaster500生物计用于测量轴向长度（AL），前房深度（ACD），角膜曲率测量（K），白色至白色(WTW)，ICLV4c植入前和植入后至少2个月的中央角膜厚度（CCT）值。使用巴雷特通用II公式计算IOL功率。
结果：该研究包括28例患者的45只眼。AL显著增加(平均0.03±0.07毫米，p=0.01），ACDs显着下降（平均0.19±0.17mm，p<0.001)基于Pentacam-AXL。在IOLMaster500中也发现了AL和ACD的类似变化。此外,两种设备中WTWs和Pentacam-AXL中CCT的差异有统计学意义。然而,两种装置的术前和术后K1和K2分别具有可比性.通过Pentacam-AXL中内置的软件或通过手动将IOLMaster500的参数手动放入公式中（分别为p=0.058，p=0.675），由BarrettUniversalII公式计算的IOL功率没有显着变化。
结论：眼部参数，包括AL，ACD,WTW,使用新型Pentacam-AXL和基于标准PCI的IOLMaster500的CCT在ICLV4c植入前后发生了显着变化，而使用BarrettUniversalII公式预测IOL功率的影响很小。
