Abstract：
BACKGROUND: Giant inflammatory polyposis (GIP) is a rare manifestation of inflammatory bowel disease (IBD), and it is described as a worm-like projection of 1.5 cm or more in diameter with unclear pathogenesis. GIP may be related to the severity of IBD. GIP presents with a wide range of symptoms, including crampy abdominal pain, anemia, and intestinal obstruction. The histopathology of GIP is a polyp lined by normal colonic mucosa with superficial ulceration that may show mild crypt distortion.
METHODS: Our case reports a patient with ulcerative colitis diagnosed via colonoscopy and histopathology 10 months before presenting with severe anemia due to lower gastrointestinal bleeding. Colonoscopy showed GIP obstructing the descending and sigmoid colon, and total colectomy showed the entire colon full of worm-like polyps up to 14 cm the longest polyp.
CONCLUSIONS: Giant inflammatory polyposis which is seen in 17 % of UC with active colitis, as seen in our patient, the histopathology component was acute in addition to chronic, which formed within 6 months. According to the data in the literature, the average duration reported for formation since diagnosis with UC is approximately 3 to 276 months. With a length up to 16 cm, the sigmoid colon is the most common site.
CONCLUSIONS: Surgical intervention is indicated for filiform polyposis (FP) if it is complicated, such as bleeding or obstruction, which is reported in a few cases. However, there are no clear guidelines for surgical intervention for complicated FP, but the safest method is to tailor the management according to the guidelines for each underlying disease.
METHODS: Our case reports a patient with ulcerative colitis diagnosed via colonoscopy and histopathology 10 months before presenting with severe anemia due to lower gastrointestinal bleeding. Colonoscopy showed GIP obstructing the descending and sigmoid colon, and total colectomy showed the entire colon full of worm-like polyps up to 14 cm the longest polyp.
CONCLUSIONS: Giant inflammatory polyposis which is seen in 17 % of UC with active colitis, as seen in our patient, the histopathology component was acute in addition to chronic, which formed within 6 months. According to the data in the literature, the average duration reported for formation since diagnosis with UC is approximately 3 to 276 months. With a length up to 16 cm, the sigmoid colon is the most common site.
CONCLUSIONS: Surgical intervention is indicated for filiform polyposis (FP) if it is complicated, such as bleeding or obstruction, which is reported in a few cases. However, there are no clear guidelines for surgical intervention for complicated FP, but the safest method is to tailor the management according to the guidelines for each underlying disease.
摘要：
背景：巨大的炎症性息肉病（GIP）是炎症性肠病（IBD）的罕见表现，它被描述为直径1.5厘米或更大的蠕虫状突起，其发病机理尚不清楚。GIP可能与IBD的严重程度有关。GIP表现出广泛的症状，包括腹部痉挛疼痛,贫血,和肠梗阻。GIP的组织病理学是由正常结肠粘膜衬里的息肉，浅表溃疡可能显示轻度隐窝变形。
方法：我们的病例报告了一名溃疡性结肠炎患者，经结肠镜检查和组织病理学诊断，10个月前由于下消化道出血而出现严重贫血。结肠镜检查显示GIP阻塞了降结肠和乙状结肠，全结肠切除术显示整个结肠充满蠕虫状息肉，最长的息肉可达14厘米。
结论：在17％的UC伴活动性结肠炎中可见巨大的炎症性息肉病，正如在我们的病人身上看到的，除慢性外，组织病理学成分是急性的，在6个月内形成。根据文献中的数据,报告的自诊断UC后形成的平均持续时间约为3~276个月.长度可达16厘米，乙状结肠是最常见的部位。
结论：丝状息肉（FP）如果复杂，则需要手术干预，如出血或梗阻，在少数情况下报道。然而,对于复杂的FP，没有明确的手术干预指南，但最安全的方法是根据每种潜在疾病的指南定制管理。
方法：我们的病例报告了一名溃疡性结肠炎患者，经结肠镜检查和组织病理学诊断，10个月前由于下消化道出血而出现严重贫血。结肠镜检查显示GIP阻塞了降结肠和乙状结肠，全结肠切除术显示整个结肠充满蠕虫状息肉，最长的息肉可达14厘米。
结论：在17％的UC伴活动性结肠炎中可见巨大的炎症性息肉病，正如在我们的病人身上看到的，除慢性外，组织病理学成分是急性的，在6个月内形成。根据文献中的数据,报告的自诊断UC后形成的平均持续时间约为3~276个月.长度可达16厘米，乙状结肠是最常见的部位。
结论：丝状息肉（FP）如果复杂，则需要手术干预，如出血或梗阻，在少数情况下报道。然而,对于复杂的FP，没有明确的手术干预指南，但最安全的方法是根据每种潜在疾病的指南定制管理。
