PDF(Pubmed)
Abstract：
This review serves as an update to the previous Nocardia review by Brown-Elliott et al. published in 2006 (B. A. Brown-Elliott, J. M. Brown, P. S. Conville, and R. J. Wallace. Jr., Clin Microbiol Rev 19:259-282, 2006, https://doi.org/10.1128/CMR.19.2.259-282.2006). Included is a discussion on the taxonomic expansion of the genus, current identification methods, and the impact of new technology (including matrix-assisted laser desorption ionization-time of flight [MALDI-TOF] and whole genome sequencing) on diagnosis and treatment. Clinical manifestations, the epidemiology, and geographic distribution are briefly discussed. An additional section on actinomycotic mycetoma is added to address this often-neglected disease.
摘要：
这篇评论是对Brown-Elliott等人先前的诺卡氏菌评论的更新。2006年出版（B.A.布朗-艾略特,J.M.布朗,P.S.康维尔,还有R.J.华莱士.Jr.,ClinMicrobiolRev19:259-282,2006,https://doi.org/10.1128/CMR.19.2.259-282.2006).包括关于该属的分类学扩展的讨论，当前的识别方法，以及新技术（包括基质辅助激光解吸电离飞行时间[MALDI-TOF]和全基因组测序）对诊断和治疗的影响。临床表现,流行病学,并简要讨论了地理分布。增加了放线菌肌瘤的另一部分，以解决这种经常被忽视的疾病。
