对 GluN1 - 2C 的组装和功能的结构见解 ,GluN1 - 2A - 2C,和 GluN1 - 2D NMDAR 。
关键词: GluN1-2A-2C tri-heteromeric NMDA receptor GluN1-2C NMDA receptor GluN1-2D NMDA receptor N-methyl-D-aspartate receptors NMDAR subtypes NMDARs PYD-106 allosteric modulation ligand-gated ion channels single-particle cryo-EM
Mesh : Humans Receptors, N-Methyl-D-Aspartate / genetics chemistry metabolism Glutamic Acid / metabolism Glycine / metabolism Synaptic Transmission Protein Subunits / metabolism
来 源:
DOI:10.1016/j.molcel.2022.10.008
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