Abstract：
UNASSIGNED: Central line complications remain a problem in critical care patient populations. Various interventions to prevent or treat complications, such as central line-associated bloodstream infection and occlusion, have been the focus of recent research. Although alternative catheter locking solutions have been shown to be effective in other patient populations, their applicability to the critical care setting remains unclear. Due to the high acuity of critical care patients, it is uncertain whether their central lines remain locked for a duration long enough for alternative locking solutions to provide any effect.
UNASSIGNED: This single-centre, prospective, observational study aimed to gather information about the length of time central line lumens remain in a locked state in the average critical care patient. Baseline rates of various central line complications were also tracked.
UNASSIGNED: Results of this study indicate that the majority of central lines will have at least one lumen locked for an average of 36.6% of their time in situ.
UNASSIGNED: It is anticipated that this length of time provides enough exposure for alternative locking solutions to potentially make a difference in central line complications in this patient population. Results of this study can be used for planning future multi-centre, randomized controlled trials investigating the efficacy of novel central line locking solutions to prevent central line complications in critically ill patients.
UNASSIGNED: This single-centre, prospective, observational study aimed to gather information about the length of time central line lumens remain in a locked state in the average critical care patient. Baseline rates of various central line complications were also tracked.
UNASSIGNED: Results of this study indicate that the majority of central lines will have at least one lumen locked for an average of 36.6% of their time in situ.
UNASSIGNED: It is anticipated that this length of time provides enough exposure for alternative locking solutions to potentially make a difference in central line complications in this patient population. Results of this study can be used for planning future multi-centre, randomized controlled trials investigating the efficacy of novel central line locking solutions to prevent central line complications in critically ill patients.
摘要：
未经证实：在重症监护患者人群中，中心管路并发症仍然是一个问题。预防或治疗并发症的各种干预措施，如中心线相关的血流感染和闭塞，一直是最近研究的重点。尽管替代导管锁定解决方案已被证明对其他患者人群有效，其对重症监护的适用性尚不清楚.由于重症监护患者的高敏锐度，不确定它们的中心线是否在足够长的时间内保持锁定，以便替代锁定解决方案提供任何效果。
未经评估：这种单中心，prospective,观察性研究旨在收集有关重症监护患者平均中心线管腔处于锁定状态的时间长度的信息。还跟踪了各种中心线并发症的基线率。
UNASSIGNED：这项研究的结果表明，大多数中心线将至少有一个管腔锁定，平均其原位时间为36.6％。
UNASSIGNED：预计该时间长度为替代锁定解决方案提供了足够的暴露量，从而可能在该患者人群中的中心线并发症中发挥作用。这项研究的结果可用于规划未来的多中心，随机对照试验研究了新型中央线锁定解决方案预防危重患者中央线并发症的功效。
未经评估：这种单中心，prospective,观察性研究旨在收集有关重症监护患者平均中心线管腔处于锁定状态的时间长度的信息。还跟踪了各种中心线并发症的基线率。
UNASSIGNED：这项研究的结果表明，大多数中心线将至少有一个管腔锁定，平均其原位时间为36.6％。
UNASSIGNED：预计该时间长度为替代锁定解决方案提供了足够的暴露量，从而可能在该患者人群中的中心线并发症中发挥作用。这项研究的结果可用于规划未来的多中心，随机对照试验研究了新型中央线锁定解决方案预防危重患者中央线并发症的功效。
