UNASSIGNED: A single center retrospective study enrolled 120 patients (mean age 52.51 ± 14.29 years) who underwent PFO closure between April 2019 and March 2021. 87 patients (72.5%) had suffered cryptogenic stroke (CS) at least one time, and 24 patients (20%) had repetitive episodes of hemicrania unsourced. 65 patients were in the transesophageal echocardiography (TEE) guidance group (T-group), and the other 55 patients were in the angiographic guidance group (A-group).
UNASSIGNED: There were no significant differences in crucial clinical characteristics between the two groups. In T-group, the procedural success rate was higher (100% vs. 92.7%, P = 0.028), and the procedural time was shorter (23.15 ± 13.87 vs. 25.75 ± 7.19, P = 0.001). No difference was detected in the procedural complication rate. Follow-up were performed at least 12 months. At 12 months, new atrial fibrillation occurred in 1 patient (1.5%) in the T-group and in 1 patient (1.8%) in the A-group (P = 0.905). Residual shunt occurred in 1 patient (1.5%) in the T-group and in 3 patients (5.5%) in the A-group (P = 0.236). Recurrent cerebral ischemia occurred in 2 patient (3.1%) in the T-group and in 2 patients (3.6%) in the A-group (P = 0.865).
UNASSIGNED: The use of only intra-procedural TEE guidance for PFO closure is safe and effective. The whole procedure can be performed without fluoroscopy and contrast medium. The short and medium follow-up results are satisfactory, especially in the residual shunt.
UNASSIGNED:一项单中心回顾性研究纳入了在2019年4月至2021年3月期间接受PFO封堵的120例患者(平均年龄52.51±14.29岁)。87例(72.5%)患者至少有1次患有隐源性卒中(CS),24例患者(20%)有反复发作的偏头痛。经食管超声心动图(TEE)指导组(T组)65例,其他55例患者在血管造影指导组(A组)。
UNASSIGNED:两组之间的关键临床特征没有显着差异。在T组,手术成功率较高(100%vs.92.7%,P=0.028),手术时间较短(23.15±13.87vs.25.75±7.19,P=0.001)。手术并发症发生率无差异。随访至少12个月。12个月时,T组1例患者(1.5%)和A组1例患者(1.8%)出现新的心房颤动(P=0.905).T组1例(1.5%)和A组3例(5.5%)发生残余分流(P=0.236)。T组2例(3.1%)和A组2例(3.6%)发生复发性脑缺血(P=0.865)。
UNASSIGNED:仅使用术中TEE指导进行PFO闭合是安全有效的。整个过程可以在没有荧光透视和造影剂的情况下进行。中短随访结果令人满意,尤其是在残余分流中。