PDF(Pubmed)
Abstract：
UNASSIGNED: The lack of knowledge regarding osteoarticular tuberculosis (TB) cases in Indonesia leads to delayed and chronic conditions. This study aims to evaluate clinical outcomes of patients with osteoarticular TB.
UNASSIGNED: Thirty osteoarticular cases were retrospectively analyzed, with a focus on non-immunocompromised patients without spine involvement. Chemotherapy length, operative treatment method, and infection recurrence were evaluated.
UNASSIGNED: The majority (60%) of patients were aged between 19 to 49 years. The most common complaint was painful swelling, particularly during physical activity. Weight-bearing joints, such as the hips, knees, and ankles, were the most affected. Laboratory results showed over half of the patients had anemia, 96% had elevated erythrocyte sedimentation rate (ESR), and 76% had elevated C-reactive protein (CRP) levels. Radiological findings varied, with lytic lesions, abscesses, and joint destruction observed. All patients presented with pathognomonic histological tubercle appearances, with caseous necrosis, lymphocytes, and Langhans giant cells present. Twenty-nine cases were treated with anti-TB drugs for 12 months, while one recurrent case received the drugs for 24 months. All patients underwent surgery to gain local infection control.
UNASSIGNED: Osteoarticular TB is a common manifestation of extrapulmonary TB and must not be overlooked. Early detection of osteoarticular TB may prevent limb morbidity. Although anti-TB drugs are the primary treatment for osteoarticular TB, in some cases, surgery is required to establish a diagnosis and gain local infection control.
UNASSIGNED: Thirty osteoarticular cases were retrospectively analyzed, with a focus on non-immunocompromised patients without spine involvement. Chemotherapy length, operative treatment method, and infection recurrence were evaluated.
UNASSIGNED: The majority (60%) of patients were aged between 19 to 49 years. The most common complaint was painful swelling, particularly during physical activity. Weight-bearing joints, such as the hips, knees, and ankles, were the most affected. Laboratory results showed over half of the patients had anemia, 96% had elevated erythrocyte sedimentation rate (ESR), and 76% had elevated C-reactive protein (CRP) levels. Radiological findings varied, with lytic lesions, abscesses, and joint destruction observed. All patients presented with pathognomonic histological tubercle appearances, with caseous necrosis, lymphocytes, and Langhans giant cells present. Twenty-nine cases were treated with anti-TB drugs for 12 months, while one recurrent case received the drugs for 24 months. All patients underwent surgery to gain local infection control.
UNASSIGNED: Osteoarticular TB is a common manifestation of extrapulmonary TB and must not be overlooked. Early detection of osteoarticular TB may prevent limb morbidity. Although anti-TB drugs are the primary treatment for osteoarticular TB, in some cases, surgery is required to establish a diagnosis and gain local infection control.
摘要：
未经评估：印度尼西亚缺乏关于骨关节结核（TB）病例的知识会导致延迟和慢性疾病。本研究旨在评估骨关节结核患者的临床预后。
UNASSIGNED：回顾性分析30例骨关节病例，重点关注无脊柱受累的非免疫功能低下患者。化疗长度，手术治疗方法,评估感染复发。
未经证实：大多数（60%）患者年龄在19至49岁之间。最常见的症状是疼痛性肿胀，特别是在体育活动中。承重接头,比如臀部，膝盖,脚踝，受影响最大。实验室结果显示，超过一半的患者患有贫血，96%的患者红细胞沉降率(ESR)升高,76％的患者C反应蛋白（CRP）水平升高。放射学发现各不相同，有溶解性病变，脓肿,并观察到联合破坏。所有患者均表现为病理组织学结节，有干酪样坏死,淋巴细胞，和存在的Langhans巨细胞。29例接受抗结核药物治疗12个月,而一名复发病例接受了24个月的药物治疗。所有患者均接受手术以获得局部感染控制。
UNASSIGNED：骨关节结核是肺外结核的常见表现，绝不能忽视。早期发现骨关节结核可预防肢体发病。虽然抗结核药物是骨关节结核的主要治疗方法，在某些情况下,需要手术来确定诊断并获得局部感染控制。
UNASSIGNED：回顾性分析30例骨关节病例，重点关注无脊柱受累的非免疫功能低下患者。化疗长度，手术治疗方法,评估感染复发。
未经证实：大多数（60%）患者年龄在19至49岁之间。最常见的症状是疼痛性肿胀，特别是在体育活动中。承重接头,比如臀部，膝盖,脚踝，受影响最大。实验室结果显示，超过一半的患者患有贫血，96%的患者红细胞沉降率(ESR)升高,76％的患者C反应蛋白（CRP）水平升高。放射学发现各不相同，有溶解性病变，脓肿,并观察到联合破坏。所有患者均表现为病理组织学结节，有干酪样坏死,淋巴细胞，和存在的Langhans巨细胞。29例接受抗结核药物治疗12个月,而一名复发病例接受了24个月的药物治疗。所有患者均接受手术以获得局部感染控制。
UNASSIGNED：骨关节结核是肺外结核的常见表现，绝不能忽视。早期发现骨关节结核可预防肢体发病。虽然抗结核药物是骨关节结核的主要治疗方法，在某些情况下,需要手术来确定诊断并获得局部感染控制。
