Abstract：
Background and objectives: Psoriasis can lead to feelings of stigmatization, hinder social functioning, and impair quality of life. Psoriasis can also affect sexual activity, but there is still little research on this topic. The present study investigated whether and to what extent psoriasis, its severity, location and extent of skin lesions affect sexual dysfunction. Materials and Methods: A total of 45 women and 64 men aged 18 to 73 years hospitalized for psoriasis exacerbations were included in the study. Psoriasis severity, as assessed by the Psoriasis Area and Severity Index (PASI), ranged from 0.2 to 65 points (mean: 17.0 ± 14.9 points). After collecting demographic and clinical data, each subject was asked to complete the Dermatology Life Quality Index, the 11-item Sexual Life Questionnaire and the International Index of Erectile Function (only men). Results: Our study found that more than 90% of the patients surveyed felt at least a slight unattractiveness due to psoriasis. In approximately 80% of the subjects, the skin lesions at least occasionally affected their sex life, and more than 50% at least sometimes avoided sexual contact. The location of psoriasis, particularly in the genital area (p = 0.01), on the face (p = 0.03) and hands (p = 0.05), also had a significant impact on the level of sexual problems. Psoriasis has a significant impact on the quality of life (QoL), and a deterioration in QoL was strongly correlated with sexual dysfunction (r = 0.6, p < 0.001), PASI scores (r = 0.36, p < 0.001), self-assessment of psoriasis severity and location of psoriatic lesions. Conclusions: Psoriasis leads to various limitations, especially in the sphere of sexual life. Patients with psoriasis feel stigmatized, have lowered self-esteem and consequently experience significant sexual problems. Awareness of the co-occurring psychological aspect of psoriasis and the routine use of validated scales in dermatology practice should contribute to the rapid identification of patients with sexual dysfunction.
摘要：
背景和目标：牛皮癣会导致污名化的感觉，阻碍社会功能，影响生活质量.牛皮癣也会影响性活动，但是关于这个话题的研究仍然很少。本研究调查了牛皮癣是否以及在多大程度上，其严重性,皮肤病变的部位和程度影响性功能障碍。材料和方法：共有45名女性和64名男性因银屑病加重住院，年龄在18至73岁之间。银屑病严重程度,根据银屑病面积和严重程度指数(PASI)评估，范围为0.2至65分（平均值：17.0±14.9分）。在收集了人口统计学和临床数据后，要求每个受试者完成皮肤病学生活质量指数，11项性生活问卷和国际勃起功能指数(仅限男性)。结果：我们的研究发现，超过90％的患者因牛皮癣而感到至少有轻微的吸引力。在大约80%的受试者中，皮肤损伤至少偶尔会影响他们的性生活，超过50%的人至少有时会避免性接触。牛皮癣的位置,特别是在生殖器区域（p=0.01），在脸上（p=0.03）和手上（p=0.05），也对性问题的程度产生了重大影响。银屑病对生活质量(QoL)有显著影响，QoL恶化与性功能障碍密切相关（r=0.6，p<0.001），PASI评分（r=0.36，p<0.001），银屑病严重程度和银屑病皮损位置的自我评估。结论：银屑病导致各种局限性，尤其是在性生活领域。牛皮癣患者感到污名化，降低了自尊，因此经历了严重的性问题。对银屑病共同发生的心理方面的认识以及在皮肤病学实践中常规使用经过验证的量表应有助于快速识别性功能障碍患者。
