Abstract：
A new formulation (suspension concentrate, SC) of PBQ [1-(4-chlorophenyl)-3-(pyridin-3-yl) urea] was used in water network schistosomiasis-endemic areas to test its molluscicidal efficacy and the acute toxicity to crustaceans. PBQ (20% SC), 26% metaldehyde, and niclosamide suspension concentrate [MNSC (26% SC)] were used both in ditch and field experiments for the molluscicidal efficacy comparison. Acute toxicity tests of two molluscicides were conducted using Neocaridina denticulate and Eriocheir sinensis. Both in the field and ditch experiments, PBQ exhibited comparable molluscicidal efficacy with MNSC. At doses of 0.50 g/m3 and 0.50 g/m2, the snail mortalities were more than 90% three days after PBQ (20% SC) application. Compared with previous tests, PBQ (20% SC) exhibited higher molluscicidal activity than PBQ (25% wettable powder, 25% WP) used in Jiangling and showed similar mollucicidal activity to PBQ (25% WP) used in Dali and Poyang Lake. The 96 h LC50 value of MNSC against Eriocheir sinensis was 283.84 mg a.i./L. At the concentration of PBQ (20% SC) 1000 mg a.i./L, all Eriocheir sinensis were alive. The 96 h LC50 values of PBQ and MNSC against Neocaridina denticulate were 17.67 and 14.05 mg a.i./L, respectively. In conclusion, PBQ (20% SC) had a comparable molluscicidal efficacy with MNSC (26% SC) and PBQ (25% WP). Furthermore, it showed lower toxicity to the crustacean species, better solubility, no floating dust, and convenience for carriage. PBQ (20% SC) was suitable for controlling snails in the water network schistosomiasis-endemic areas.
摘要：
一种新的配方(悬浮浓缩物，SC）的PBQ[1-（4-氯苯基）-3-（吡啶-3-基）脲]用于水网血吸虫病流行地区，以测试其杀软体动物的功效和对甲壳类动物的急性毒性。PBQ（20%SC），26%的乙醛，和氯硝柳胺悬浮浓缩物[MNSC（26％SC）]用于沟渠和田间试验，以比较杀软体动物的功效。对两种杀软体动物进行了急性毒性试验。在野外和沟渠实验中，PBQ表现出与MNSC相当的杀软体动物功效。在0.50g/m3和0.50g/m2的剂量下，施用PBQ（20％SC）后三天，蜗牛死亡率超过90％。与以前的测试相比，PBQ(20%SC)比PBQ(25%可湿性粉剂,江陵使用的25％WP）与大理和鄱阳湖使用的PBQ（25％WP）具有相似的杀霉菌活性。MNSC对中华绒螯蟹的96hLC50值为283.84mga.i./L。在PBQ浓度(20%SC)1000mga.i./L时，所有中华绒螯蟹都活着。PBQ和MNSC对新小齿的96hLC50值分别为17.67和14.05mga.i./L，分别。总之,PBQ(20%SC)具有与MNSC(26%SC)和PBQ(25%WP)相当的杀软体动物功效。此外，它对甲壳类动物的毒性较低，更好的溶解度，没有浮尘，和运输方便。PBQ（20％SC）适用于控制水网血吸虫病流行区的蜗牛。
